新型天然杨梅素具有 AIE 和 ESIPT 特性，可用于体外和体内超氧阴离子的选择性检测和成像。
Novel natural myricetin with AIE and ESIPT characteristics for selective detection and imaging of superoxide anions in vitro and in vivo.
机构信息
Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China.
出版信息
Chem Commun (Camb). 2019 Sep 10;55(73):10912-10915. doi: 10.1039/c9cc05212g.
PMID:31441468
Abstract
A novel AIE probe with ESIPT characteristics, myricetin, has been easily purified from vine tea for reversible, selective and sensitive targeting of O2˙- in turn-on mode. Its AIE nanocrystals exhibit large Stokes shift, high photostability, excellent biocompatibility, and low cytotoxicity for endogenous O2˙- detection and imaging in vitro and in vivo.
摘要
一种具有 ESIPT 特性的新型 AIE 探针，杨梅素，已从藤茶中被轻易地纯化出来，可用于以开关模式对 O2˙-进行可逆、选择性和灵敏的靶向。其 AIE 纳米晶体具有大斯托克斯位移、高光稳定性、优异的生物相容性和低细胞毒性，可用于体外和体内内源性 O2˙-的检测和成像。
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