Department of General Surgery, Assuta Medical Center, Tel-Aviv, Israel.
Department of Nutrition, Assuta Medical Center, Tel-Aviv, Israel.
PLoS One. 2019 Aug 27;14(8):e0221576. doi: 10.1371/journal.pone.0221576. eCollection 2019.
To determine the impact of sleeve gastrectomy in patients suffering from depression compared with those who are not in a depressive state.
Obesity is considered a global epidemic. Often patients with obesity suffer from depressive state. Depressive disorders may be both a cause and a consequence of obesity.
The study includes 300 consecutives patients that underwent laparoscopic sleeve gastrectomy. Out of the 300 patients, 253 (84.33%) of them completed the follow up for three years.
Out of the 300-patients, with the average age of 41.65±11.05 years old, the ratio of males to females was 1:2. The average baseline BMI was 42.02 kg/m2. A total of 105 (35.33%) of the patients suffer from depression, which was more common in male (43%) than in female (31.5%), with statistically significant difference (p = .05). Comparing the weight loss after surgery in both groups, the mean weight loss in the depression-group was 12.0 ΔBMI and in the non-depression group was 13.03 ΔBMI, (p< .001). After three years, 94 (88.68%) patients of the depression group responded as they were optimistic and satisfied with the results of the operation, with positive changes in their lives, 8 (7.55%) did not experience change and 4 (3.77%) expressed to have worsened their depressive state.
Laparoscopic sleeve gastrectomy is successful and leads to weight loss even in subjects who are affected by depression syndrome.
比较患有抑郁症和非抑郁状态的患者行袖状胃切除术的效果。
肥胖症被认为是一种全球性的流行疾病。通常,肥胖症患者会伴有抑郁状态。抑郁障碍可能既是肥胖的原因,也是肥胖的结果。
本研究纳入了 300 例连续接受腹腔镜袖状胃切除术的患者。在这 300 例患者中,有 253 例(84.33%)完成了 3 年的随访。
在这 300 例患者中,平均年龄为 41.65±11.05 岁,男女比例为 1:2。平均基线 BMI 为 42.02kg/m2。共有 105 例(35.33%)患者患有抑郁症,其中男性(43%)比女性(31.5%)更为常见,差异有统计学意义(p=0.05)。比较两组患者术后的体重减轻情况,抑郁组的平均体重减轻量为 12.0ΔBMI,非抑郁组为 13.03ΔBMI,差异有统计学意义(p<0.001)。3 年后,抑郁组 94 例(88.68%)患者对手术结果表示乐观和满意,生活发生积极变化,8 例(7.55%)无变化,4 例(3.77%)表示抑郁状态恶化。
腹腔镜袖状胃切除术是成功的,即使在患有抑郁综合征的患者中也能导致体重减轻。