Estifan Elias, Nanavati Sushant M, Kumar Vinod, Gibiezaite Sandra, Michael Patrick
Department of Internal Medicine, St. Joseph's University Medical Center, New York Medical College, Paterson, NJ, USA.
Department of Endocrinology, St. Joseph's University Medical Center, New York Medical College, Paterson, NJ, USA.
AME Case Rep. 2019 Jul 29;3:27. doi: 10.21037/acr.2019.07.04. eCollection 2019.
Hyponatremia is an expected electrolyte resultant in diabetic ketoacidosis (DKA) that presents secondary to the dilutional effect of hyperglycemia. However, hypernatremia in DKA is a rare presentation, more common in the pediatric population, that rides poor morbidity and mortality. We describe three cases of patients presenting with DKA and hypernatremia with altered sensorium and share details on pathophysiology and treatment that expand our understanding amongst clinicians.
低钠血症是糖尿病酮症酸中毒(DKA)中预期出现的一种电解质异常,继发于高血糖的稀释作用。然而,DKA中的高钠血症是一种罕见表现,在儿科人群中更常见,且发病率和死亡率较高。我们描述了3例出现DKA和高钠血症且伴有意识改变的患者病例,并分享了有关病理生理学和治疗的细节,以增进临床医生对此的理解。