抗 TNF-α 治疗的强直性脊柱炎患者跟腱的应变超声弹性成像：初步研究。
Strain Ultrasound Elastography in the Achilles Tendon of Ankylosing Spondylitis Patients Treated With Anti-TNF-α: A Preliminary Study.
机构信息
Internistic Ultrasound Service "Campus Bio-Medico" University, Rome, Italy
Internistic Ultrasound Service "Campus Bio-Medico" University, Rome, Italy.
出版信息
In Vivo. 2019 Sep-Oct;33(5):1635-1640. doi: 10.21873/invivo.11648.
BACKGROUND/AIM: To compare patients affected by ankylosing spondylitis (AS) treated with anti-TNF-α for two years with controls in terms of Achilles tendon stiffness, ultrasound structure and thickness.
PATIENTS AND METHODS
B-mode ultrasound evaluation and strain ultrasound elastography were performed in longitudinal and transverse planes on 22 Achilles tendons of 11 AS patients and 26 of 13 controls.
RESULTS
There were no significant differences in thickness and stiffness of the Achilles tendon between AS patients and controls, except for an increased thickness in the middle third of the tendon in the AS patients (p=0.04). The Achilles tendon stiffness ratio of AS patients was 1.02±0.36 vs. 1.14±0.38 in the controls (p=0.2).
CONCLUSION
AS patients had an Achilles tendon thickness greater than controls at the middle third, but no difference in the stiffness was found among them. Strain ultrasound elastography may be useful to exclude early changes in mechanical properties of tendons.
背景/目的：比较接受抗 TNF-α 治疗两年的强直性脊柱炎（AS）患者与对照组在跟腱僵硬度、超声结构和厚度方面的差异。
患者与方法
对 11 例 AS 患者和 13 例对照组的 22 条跟腱进行了纵向和横向的 B 型超声评估和应变超声弹性成像。
结果
除了 AS 患者的跟腱中段厚度增加（p=0.04）外，AS 患者与对照组的跟腱厚度和僵硬度无显著差异。AS 患者的跟腱僵硬度比值为 1.02±0.36，对照组为 1.14±0.38（p=0.2）。
结论
AS 患者的跟腱中段厚度大于对照组，但两者的僵硬度无差异。应变超声弹性成像可能有助于排除肌腱力学性质的早期变化。
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