Area of Toxicology, Department of Health Sciences, Faculty of Veterinary, University of Murcia, Campus de Espinardo, 30100, Murcia, Spain.
Laboratory of Toxicology, Biomedical Research Institute of Murcia (IMIB-Arrixaca), University of Murcia, Murcia, Spain.
Bull Environ Contam Toxicol. 2019 Oct;103(4):521-527. doi: 10.1007/s00128-019-02697-9. Epub 2019 Aug 31.
We determinated Hg and Se concentrations in liver, kidney, brain, lung and muscle of five bottlenose dolphin (Tursiops truncatus), four common dolphins (Delphinus delphis) and four Risso's dolphin (Grampus griseus) stranded along the Murcia coast, Southeast Spain, in order to evaluate the risk of Hg toxicity. Hg concentrations showed similar concentrations to other individuals in the Mediterranean Sea with the same length in the same period. We observed a positive correlation of Hg and Se in liver (r = 0.948, p < 0.001) and kidney (r = 0.939; p = 0.001) and ratio the Se/Hg molar was higher than 1 in most cases. Our results suggest that the protective effects of Se against Hg toxicity occur in cetaceans. However, we detected levels of Hg described as responsible liver damage and neurotoxicological effects so other tools, as biochemical markers, should be included. Besides, more studies are needed to evaluate the risk of Hg exposure in dolphins from Murcia coastline.
我们测定了 5 头宽吻海豚(Tursiops truncatus)、4 头海豚(Delphinus delphis)和 4 头灰海豚(Grampus griseus)肝脏、肾脏、大脑、肺和肌肉中的汞和硒浓度,以评估汞毒性的风险。这些浓度与同一时期、同一地区的地中海其他个体相似。我们观察到肝脏(r = 0.948,p < 0.001)和肾脏(r = 0.939;p = 0.001)中汞和硒呈正相关,并且在大多数情况下硒/汞摩尔比高于 1。我们的结果表明,硒对汞毒性的保护作用在鲸目动物中发生。然而,我们检测到了被认为会导致肝脏损伤和神经毒性的汞水平,因此应该包括其他工具,如生化标志物。此外,还需要更多的研究来评估默里亚沿海海豚暴露于汞的风险。