Tye Marc, Masino Mark A
Department of Neuroscience, University of Minnesota Twin-Cities Minneapolis, MN 55455, USA.
Toxics. 2019 Sep 7;7(3):46. doi: 10.3390/toxics7030046.
Dietary contaminants are often an over-looked factor in the health of zebrafish. Typically, water is considered to be the source for most contaminants, especially within an aquatic environment. For this reason, source water for zebrafish recirculating systems is highly regulated and monitored daily. Most facilities use reverse osmosis or de-ionized water filtration systems to purify incoming water to ensure that contaminants, as well as pathogens, do not enter their zebrafish housing units. However, diets are rarely tested for contaminants and, in the case of manufactured zebrafish feeds, since the product is marketed for aquaculture or aquarium use it is assumed that the feed is acceptable for animals used for research. The following provides examples as to how contaminants could lead to negative effects on development and behavior of developing zebrafish.
饮食污染物常常是斑马鱼健康中一个被忽视的因素。通常,水被认为是大多数污染物的来源,尤其是在水生环境中。因此,斑马鱼循环系统的源水受到严格监管且每日进行监测。大多数设施使用反渗透或去离子水过滤系统来净化进水,以确保污染物以及病原体不会进入它们的斑马鱼养殖单元。然而,很少对饲料进行污染物检测,而且对于人工制造的斑马鱼饲料而言,由于该产品是面向水产养殖或水族箱使用进行销售的,所以假定这种饲料对于用于研究的动物是可接受的。以下列举了一些污染物如何对发育中的斑马鱼的发育和行为产生负面影响的例子。