Laboratorial Haematology Department, Portuguese Institute of Oncology of Porto , Porto, Portugal.
Platelets. 2020 May 18;31(4):541-543. doi: 10.1080/09537104.2019.1664733. Epub 2019 Sep 13.
Thrombocytopenia is a clinically important condition that can lead to several problems when not correctly diagnosed. A decrease of platelet counts due to an phenomenon, Pseudothrombocytopenia, can be misunderstood and unnecessarily treated. The present case study describes a 57-year-old male with a history of pancreas adenocarcinoma and a current infection without any signs or symptoms that could explain the low levels of platelets obtained after blood analysis. Blood smear evaluation detected both platelet satellitism and phagocytosis by neutrophils. As this sample was anticoagulated with ethylenediaminetetraacetic acid (EDTA), a new blood sample with citrate was analyzed. Platelet count was normal and no morphological abnormalities were detected. This case emphasizes the need for considering not only laboratory results but also the patient clinical information to guarantee the correct diagnosis and the best treatment possible.
血小板减少症是一种临床重要的病症,如果不能正确诊断,可能会导致多种问题。由于假性血小板减少症等现象导致血小板计数减少,可能会被误解,并进行不必要的治疗。本病例研究描述了一名 57 岁男性,患有胰腺腺癌,目前感染,但没有任何迹象或症状可以解释血液分析后获得的低血小板水平。血涂片评估发现血小板卫星现象和中性粒细胞吞噬作用。由于该样本用乙二胺四乙酸(EDTA)抗凝,因此分析了新的柠檬酸盐抗凝样本。血小板计数正常,未发现形态异常。本病例强调不仅需要考虑实验室结果,还需要考虑患者的临床信息,以确保正确诊断和尽可能最佳的治疗。