Malik Azeem Tariq, Quatman Carmen E, Phieffer Laura S, Ly Thuan V, Khan Safdar N
Department of Orthopaedics, The Ohio State University Wexner Medical Center, USA.
J Clin Orthop Trauma. 2019 Sep-Oct;10(5):904-911. doi: 10.1016/j.jcot.2018.10.020. Epub 2018 Oct 28.
Despite abundant literature present on complications following hip fracture surgery, few studies have focused on the timing of these complications.
The 2015-2016 American College of Surgeons - National Surgical Quality Improvement Program database was queried for patients ≥65 years of age undergoing hip fracture surgery, due to trauma, using CPT-Codes for total hip arthroplasty (27130), Hemiarthroplasty (27125) and Open Reduction/Internal Fixation (ORIF) (27236, 27244, 27245). For each complication being studied, the median time to diagnosis was determined along with the interquartile range (IQR). Cox-regression analyses were used to assess complication timings between various surgeries.
A total of 31,738 were included in the final cohort. The median time of occurrence (days) for myocardial infarction was 2 [IQR 1-6], pneumonia 4 [IQR 2-12], stroke/CVA 3 [IQR 1-10], pulmonary embolism 5 [IQR 2-14], urinary tract infection (UTI) 8 [IQR 2-15], deep venous thrombosis (DVT) 9 [IQR 4-17], sepsis 11 [IQR 5-19], death 12 [IQR 6-20], superficial surgical site infection (SSI) 16 [IQR 12-22], deep SSI 23 [IQR 15-24] and organ/space SSI 19 [IQR 15-23]. Undergoing a THA vs. ORIF for hip fracture was associated a relatively early occurrence of pneumonia (day 3 [IQR 1-5.25]; p = 0.029) and urinary tract infection (day 4 [IQR 1-13]; p = 0.035) and a later occurrence of organ/space SSI (day 23.5 [IQR 19.5-26.75]; p = 0.002).
Orthopaedic trauma surgeons can utilize this data to optimize care strategies during the time-periods of highest risk to prevent complications from occurring early on in the course of post-operative care.
尽管有大量关于髋部骨折手术后并发症的文献,但很少有研究关注这些并发症的发生时间。
查询2015 - 2016年美国外科医师学会 - 国家外科质量改进计划数据库,以获取年龄≥65岁因创伤接受髋部骨折手术的患者,使用全髋关节置换术(CPT编码27130)、半髋关节置换术(27125)和切开复位内固定术(ORIF,编码27236、27244、27245)的相关信息。对于每种研究的并发症,确定诊断的中位时间以及四分位间距(IQR)。采用Cox回归分析评估不同手术之间并发症的发生时间。
最终队列共纳入31,738例患者。心肌梗死发生的中位时间(天)为2[IQR 1 - 6],肺炎为4[IQR 2 - 12],中风/脑血管意外为3[IQR 1 - 10],肺栓塞为5[IQR 2 - 14],尿路感染(UTI)为8[IQR 2 - 15],深静脉血栓形成(DVT)为9[IQR 4 - 17],脓毒症为11[IQR 5 - 19],死亡为12[IQR 6 - 20],浅表手术部位感染(SSI)为16[IQR 12 - 22],深部SSI为23[IQR 15 - 24],器官/腔隙SSI为19[IQR 15 - 23]。髋部骨折接受全髋关节置换术与切开复位内固定术相比,肺炎(第3天[IQR 1 - 5.25];p = 0.029)和尿路感染(第4天[IQR 1 - 13];p = 0.035)的发生相对较早,而器官/腔隙SSI的发生较晚(第23.5天[IQR 19.5 - 26.75];p = 0.002)。
骨科创伤外科医生可利用这些数据优化术后护理高风险期的护理策略,以预防术后早期并发症的发生。