Saeed Tamar, Bashir Jawad, Hameed Fawad
Endocrinology, Diabetes and General Internal Medicine, Oxford University Hospitals NHS Trust, Oxford.
University Hospital Wales, Cardiff.
J Ayub Med Coll Abbottabad. 2019 Jul-Sep;31(3):469-471.
A 39-year-old gentleman presented to emergency department with a few hours' history of acute shortness of breath, cough and haemoptysis that developed whilst welding a steel tank in a closed container. He was welder by profession for thirteen years with no significant past medical history. The arterial blood gas showed severe oxygenation impairment and he was intubated for mechanical ventilation. The radiographs showed bilateral widespread interstitial shadowing. The echocardiography showed normal heart and ruled out cardiogenic pulmonary oedemic. The microbiological investigations were all normal. He was treated as Acute Respiratory Distress Syndrome (ARDS) secondary to exposure to welding metal fumes in a closed container. He was given limited tidal volume invasive ventilation, extubated successfully after twelve days, transferred to respiratory ward for rehabilitation and discharged few days later. Exposure to welding metal fumes at work place is a major occupational health hazard worldwide. It can cause ARDS and other respiratory illnesses such as bronchitis, metal fumes fever and chronic pneumonitis. The pathogenesis of ARDS due to welding metal fumes involves direct inhalational injury and/or immune system dysfunction. Welding metal fumes related ARDS remains the diagnosis of exclusion and all other causes must be ruled out. The key to treatment is ventilation support with early endotracheal intubation. Appropriate precautionary measures are advised to avoid occupational health hazards in welding profession.
一名39岁男性因在封闭容器中焊接钢罐时出现数小时急性呼吸急促、咳嗽和咯血症状,被送往急诊科。他从事焊工工作13年,既往无重大病史。动脉血气分析显示严重的氧合障碍,遂行气管插管进行机械通气。胸部X光片显示双侧广泛的间质性阴影。超声心动图显示心脏正常,排除心源性肺水肿。微生物学检查均正常。他被诊断为在封闭容器中接触焊接金属烟雾继发的急性呼吸窘迫综合征(ARDS)。给予小潮气量有创通气,12天后成功脱机,转至呼吸病房康复,数日后出院。在工作场所接触焊接金属烟雾是全球主要的职业健康危害。它可导致ARDS和其他呼吸系统疾病,如支气管炎、金属烟雾热和慢性肺炎。焊接金属烟雾所致ARDS的发病机制涉及直接吸入损伤和/或免疫系统功能障碍。焊接金属烟雾相关ARDS仍需排除其他所有病因后才能确诊。治疗的关键是早期气管插管进行通气支持。建议采取适当的预防措施以避免焊接行业中的职业健康危害。