酷似恶性肿瘤的罕见组织学类型的肺肿物：氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描表现

Lung Masses of Unusual Histologies Mimicking Malignancy: Flurodeoxyglucose Positron Emission Tomography-Computed Tomography Appearance.

作者信息

Mathew Boon, Purandare Nilendu C, Shah Sneha, Puranik Ameya, Agrawal Archi, Rangarajan Venkatesh

机构信息

Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, Maharashtra, India.

出版信息

Indian J Nucl Med. 2019 Oct-Dec;34(4):295-301. doi: 10.4103/ijnm.IJNM_116_19.

DOI:10.4103/ijnm.IJNM_116_19

PMID:31579235

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6771216/

Abstract

18F flurodeoxyglucose positron emission tomography-computed tomography (18F FDG PET-CT) is widely used in the evaluation of patients with lung mass suspicious for malignancy. In addition to malignancy, a variety of benign neoplasms and inflammatory lesions can arise in the lungs, many of which show increased FDG concentration, thereby mimicking malignancy. Awareness of the common mimics of lung cancer and a thorough understanding of their key imaging characteristics on CT as well as FDG PET is helpful in narrowing the differential diagnosis, eventually leading to appropriate therapy. In this article, we enlist these mimics and discuss their metabolic and morphologic characteristics and provide a pathophysiological basis for their FDG uptake.

摘要

18F氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描（18F FDG PET-CT）广泛应用于对疑似恶性肺肿块患者的评估。除了恶性肿瘤外，肺部还可出现多种良性肿瘤和炎性病变，其中许多表现为FDG浓度升高，从而酷似恶性肿瘤。了解肺癌的常见模仿病变，并深入理解其在CT以及FDG PET上的关键影像特征，有助于缩小鉴别诊断范围，最终实现恰当治疗。在本文中，我们列举这些模仿病变，讨论其代谢和形态学特征，并为其FDG摄取提供病理生理基础。