Puig L, Moreno A, Domingo P, Llistosella E, de Moragas J M
J Am Acad Dermatol. 1985 May;12(5 Pt 2):961-4. doi: 10.1016/s0190-9622(85)70123-5.
POEMS syndrome is an unusual plasma cell dyscrasia with multisystemic manifestations featuring polyneuropathy, organomegaly, endocrinopathy, M protein and constant skin involvement. We have seen a 58-year-old white man presenting with generalized eruptive angiomas as a rare skin manifestation of this syndrome. We review the literature and discuss the pathogenesis of vascular proliferation in this unusual entity.
POEMS综合征是一种罕见的浆细胞病,具有多系统表现,特征为多发性神经病、器官肿大、内分泌病、M蛋白血症及持续性皮肤病变。我们诊治了一名58岁白人男性,其以泛发性暴发性血管瘤作为该综合征罕见的皮肤表现。我们回顾了相关文献并探讨了这一罕见疾病中血管增殖的发病机制。