Moshirfar Majid, Liu Harry Y, Rosen David B, Heiland Madeline B, Mirghorbani Masoud, Ronquillo Yasmyne C, Hoopes Phillip C
John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, School of Medicine, University of Utah Salt Lake City, UT, USA.
Utah Lions Eye Bank, Murray, UT, USA.
Med Hypothesis Discov Innov Ophthalmol. 2019 Fall;8(3):134-138.
Laser-Assisted in Situ Keratomileusis (LASIK) is a common surgery for the correction of refractive errors. The majority of patients who undergo this procedure often have excellent results. However, uncontrolled autoimmune disorders and dry eye have both been listed as contraindications to this surgery. Lichen planus (LP) is an autoimmune, inflammatory disorder that characteristically affects mucocutaneous membranes. The etiology is unknown, but it most commonly affects middle-aged adults and presents with bilateral, purple papules. Clinical presentation is used to diagnose the condition, and a punch biopsy is confirmatory. LP may present with multiple different symptoms depending on the type, with ocular manifestations being rare. Multiple viruses and autoimmune conditions have been associated with the disorder, and physicians should take care when gathering a full history of the patient. Exacerbation of symptoms may happen if mood disorders such as depression and anxiety are not well controlled. There are several additional factors physicians must carefully consider before recommending LASIK to patients with LP. These include lichenoid reactions, current medications, and past or present ocular lesions. LASIK may be carefully considered in patients with well-controlled LP in the absence of ocular manifestations. Patients with ocular LP are not candidates for LASIK.
准分子原位角膜磨镶术(LASIK)是一种矫正屈光不正的常见手术。大多数接受该手术的患者通常都能取得良好效果。然而,未控制的自身免疫性疾病和干眼症均被列为该手术的禁忌证。扁平苔藓(LP)是一种自身免疫性炎症性疾病,其特征是影响黏膜皮肤。病因不明,但最常见于中年成年人,表现为双侧紫色丘疹。临床表现用于诊断该病,组织活检可确诊。根据类型不同,LP可能会出现多种不同症状,眼部表现较为罕见。多种病毒和自身免疫性疾病与该病有关,医生在全面了解患者病史时应格外小心。如果抑郁和焦虑等情绪障碍未得到良好控制,症状可能会加重。在向LP患者推荐LASIK之前,医生还必须仔细考虑几个额外因素。这些因素包括苔藓样反应、当前用药情况以及过去或现在的眼部病变。在没有眼部表现且LP病情得到良好控制的患者中,可以谨慎考虑LASIK。有眼部LP的患者不适合做LASIK。