Qu Junyan, Huang Yimei, Lv Xiaoju
Center of Infectious Disease, West China Hospital, Sichuan University, Chengdu, China.
College of Pharmacy, University of Florida, Gainesville, FL, United States.
Front Microbiol. 2019 Sep 27;10:2240. doi: 10.3389/fmicb.2019.02240. eCollection 2019.
The crisis of antimicrobial resistance is worsening and has become a major public safety problem in China, seriously endangering human and animal health and ecological environment. Gram-negative bacterial resistance in China is severe: the related pathogens mainly include carbapenem-resistant and Surging antimicrobial consumption and irrational use of antimicrobials are the main causes of resistance. In China, a variety of strategies are implemented to control the antimicrobial resistance in hospitals, agriculture and environment. However, there is still a long way to go to strengthen the drug resistance surveillance, to reduce the emergence of drug-resistant bacteria, and to find new antimicrobials and therapies for drug-resistant bacteria. Controlling the antimicrobial resistance crisis takes great efforts from the whole society.
抗菌药物耐药性危机正在恶化，已成为中国的一个重大公共安全问题，严重危害人类、动物健康及生态环境。中国革兰氏阴性菌耐药情况严峻：相关病原体主要包括耐碳青霉烯类……抗菌药物的大量使用及不合理使用是耐药性的主要成因。中国实施了多种策略来控制医院、农业及环境中的抗菌药物耐药性。然而，在加强耐药性监测、减少耐药菌出现以及寻找针对耐药菌的新型抗菌药物和治疗方法方面，仍有很长的路要走。控制抗菌药物耐药性危机需要全社会付出巨大努力。 （注：原文“carbapenem-resistant and Surging antimicrobial consumption”中“and Surging antimicrobial consumption”部分表述不完整且有拼写错误，推测可能影响准确理解，但按要求未做修改直接翻译）
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