Carus T, Pick P
Klinik für Allgemein-, Visceral- und Gefäßchirurgie, Elisabeth-Krankenhaus, Klosterstr. 4, 49832, Thuine, Deutschland.
Klinik für Allgemein‑, Visceral- und Gefäßchirurgie, Asklepios Westklinikum Hamburg, Hamburg, Deutschland.
Chirurg. 2019 Nov;90(11):887-890. doi: 10.1007/s00104-019-01042-4.
Fluorescence angiography with indocyanine green (ICG-FA) is frequently used in colorectal surgery to assess the blood perfusion in the region of an anastomosis. Previous studies with ICG-FA in both open and laparoscopic surgery could show a low rate of anastomotic leakage, e.g. the PILLAR II study with a leakage rate of 1.4%. This article presents own results, the current status of ICG-FA and the fields of application.
The aim of the study was to analyze whether the results obtained so far with ICG-FA are sufficient to recommend an extended use of this relatively new method in colorectal surgery.
From July 2009 to June 2019 a total of 378 colorectal resections (280 colon resections and 98 rectal resections) with intraoperative examination of the anastomosis using ICG-FA were performed. In 13 patients (3.4%) there was reduced intraoperative perfusion, which led to a change in the operative procedure (resection of the anastomosis and new anastomosis, colostomy).
The total anastomotic leakage rate was 3.7% with 8 leaks in the colon (2.9%) and 6 in the rectum (6.1%). Without the intraoperative change in 13 patients the rate of leakages could have increased to 7.1% (27/378). The use of ICG-FA in the group of patients studied potentially led to a reduction of the leakage rate by 48%. Current publications show similar results with a potential decrease in the rate of anastomotic leaks in colorectal surgery.
The results show a very low rate of anastomotic leakage when using ICG-FA. These results are promising in colorectal surgery but controlled randomized studies are lacking and should be carried out before final recommendations can be given.
吲哚菁绿荧光血管造影术(ICG-FA)常用于结直肠手术,以评估吻合口区域的血液灌注情况。此前在开放手术和腹腔镜手术中使用ICG-FA的研究显示吻合口漏发生率较低,例如PILLAR II研究的漏出率为1.4%。本文介绍了自身研究结果、ICG-FA的现状及其应用领域。
本研究旨在分析目前ICG-FA所获结果是否足以推荐在结直肠手术中扩大使用这一相对较新的方法。
2009年7月至2019年6月,共进行了378例结直肠切除术(280例结肠切除术和98例直肠切除术),术中使用ICG-FA检查吻合口。13例患者(3.4%)术中灌注减少,这导致了手术方式的改变(切除吻合口并重新吻合、结肠造口术)。
总的吻合口漏发生率为3.7%,其中结肠漏8例(2.9%),直肠漏6例(6.1%)。若不包括13例术中改变手术方式的患者,漏出率可能会升至7.1%(27/378)。在本研究的患者组中使用ICG-FA可能使漏出率降低了48%。目前的出版物显示了类似结果,结直肠手术中吻合口漏发生率可能降低。
结果显示使用ICG-FA时吻合口漏发生率非常低。这些结果在结直肠手术中很有前景,但缺乏对照随机研究,在给出最终建议之前应开展此类研究。