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[利用γ闪烁照相机对眼内病变进行非接触式检测]

[Noncontact detection of intraocular lesions by means of a gamma scintillation camera].

作者信息

Bockslaff H, Dausch D, Bornemann H, Stöppler L, Hundeshagen H

出版信息

Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1979 Sep;211(3):187-203. doi: 10.1007/BF02387424.

Abstract

A gamma scintillation camera is used for noncontact detection of intraocular mass lesions. A double aperture pinhole collimator was designed for this special application. The collimator projects a magnified image of the radioactivity present in each eye onto the detector crystal of the camera. Details of the collimator design are described. The image-making properties of a double aperture pinhole collimator for ocular scintigraphy in regard to resolution and response were studied and demonstrated by phantom experiments. So far we have studied 50 cases with this new nuclear medicine procedure, using mainly technetium-pertechnetate as the radioindicator. Case histories and records of some typical results are presented. Better designed radiopharmaceuticals with appropriate tumor-seeking properties should be developed. Labeled melanin precursors are promising for detection of these lesions.

摘要

γ闪烁照相机用于眼内肿块病变的非接触式检测。为此特殊应用设计了一种双孔径针孔准直器。该准直器将每只眼中存在的放射性放大图像投射到相机的探测器晶体上。描述了准直器设计的细节。通过模型实验研究并证明了用于眼部闪烁显像的双孔径针孔准直器在分辨率和响应方面的成像特性。到目前为止,我们已经用这种新的核医学程序研究了50例病例,主要使用高锝酸盐作为放射性示踪剂。给出了一些典型结果的病例史和记录。应开发设计更好、具有适当肿瘤靶向特性的放射性药物。标记的黑色素前体在检测这些病变方面很有前景。

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