Pokhrel Sushant, Shrestha Sneha, Timilsina Alaska, Sapkota Manisha, Bhatt Mahendra Prasad, Pardhe Bashu Dev
Department of Laboratory Medicine, Manmohan Memorial Institute of Health Sciences, Kathmandu, Nepal.
J Multidiscip Healthc. 2019 Oct 9;12:817-826. doi: 10.2147/JMDH.S216842. eCollection 2019.
The patient believes in adherence to medication rather than to self-care adherence and lifestyle changes for the management of diabetes. This study was carried out to establish the association of self-care adherence and their barriers in poor glycemic control in our diabetic population.
This cross-sectional study was conducted among 480 already diagnosed diabetes outpatients attended in our two hospitals. Glycaemic control was defined by levels of HbA Socio-demographic data, lifestyle variables and anthropometric measurements were recorded using a standard questionnaire. Fasting blood glucose, HbA and lipid profiles were estimated using the manufacturer's guideline. Student's -test and one-way ANOVA were used for comparison between different groups and the correlation was established by Spearman correlation. Risk factors associated with poor glycaemic control were verified by logistic regression analysis.
The mean HbA of the study population was 7.4±1.3% and 65.4% had poor glycaemic control with mean 8.0±1.1%. Higher HbA levels were significantly associated with duration of diabetes, a number of drugs used, patient-physician relationship and knowledge about diabetes. The poor glycaemic control was significantly associated with low adherence of following the meal plan, regular medication and regular exercising (p<0.001). Among all the barriers, a too busy schedule for following the meal plan, taking medications and exercising regularly was significantly correlated with HbA1c levels. Multivariable logistic regression analysis showed irregular meal plan (OR=5.27), irregular exercise (OR=2.25), number of medication used (OR= 0.19) and lesser extent patient-physician relationship (OR=2.68) were independent risk factors for poor glycaemic control.
The poor glycaemic control was associated with poor adherence to self-care adherence and their barriers in our diabetic population. Integrated knowledge on diabetes management should be targeted to improve glycaemic control in our communities.
该患者认为控制糖尿病应坚持用药,而非自我护理依从性和生活方式改变。本研究旨在确定自我护理依从性及其障碍与我们糖尿病患者群体血糖控制不佳之间的关联。
本横断面研究在我们两家医院就诊的480名已确诊糖尿病门诊患者中进行。血糖控制通过糖化血红蛋白(HbA)水平定义。使用标准问卷记录社会人口统计学数据、生活方式变量和人体测量数据。按照制造商指南估算空腹血糖、糖化血红蛋白和血脂谱。采用学生t检验和单因素方差分析对不同组进行比较,并通过Spearman相关性分析确定相关性。通过逻辑回归分析验证与血糖控制不佳相关的危险因素。
研究人群的平均糖化血红蛋白为7.4±1.3%,65.4%的患者血糖控制不佳,平均糖化血红蛋白为8.0±1.1%。较高的糖化血红蛋白水平与糖尿病病程、用药数量、医患关系及糖尿病知识显著相关。血糖控制不佳与饮食计划、规律用药和规律锻炼的依从性低显著相关(p<0.001)。在所有障碍中,因日程太忙而无法遵循饮食计划、规律用药和锻炼与糖化血红蛋白水平显著相关。多变量逻辑回归分析显示,不规律的饮食计划(比值比=5.27)、不规律的锻炼(比值比=2.25)、用药数量(比值比=0.19)以及医患关系较差(比值比=2.68)是血糖控制不佳的独立危险因素。
在我们的糖尿病患者群体中,血糖控制不佳与自我护理依从性差及其障碍有关。应针对糖尿病管理的综合知识,以改善我们社区的血糖控制。