Department of Rehabilitation, Kobe City Nishi-Kobe Medical Centre, 5-7-1, Kojidai, Nishiku, Kobe, Hyogo, Japan.
Konan Women's University, Faculty of Nursing and Rehabilitation, 2-23-6, Morikita-machi, Higashinadaku, Kobe, Japan.
Injury. 2019 Dec;50(12):2272-2276. doi: 10.1016/j.injury.2019.10.011. Epub 2019 Oct 5.
Many hip fracture patients have decreased functional status inhibiting recovery to pre-fracture functional status. The prevalence of frailty in patients with hip fracture is high, but little is known how frailty is associated with functional recovery. The aim of this study was to determine whether frailty can predict functional recovery and clinical outcomes during the acute phase in hip fracture.
This study was retrospective observational study from two acute hospitals. Participants were recruited from hip fracture patients who underwent surgery. The main exposure was frailty defined using 19-item modified Frailty Index (mFI). The main outcome was functional recovery, evaluated by postoperative efficiency on the motor-Functional Independence Measure (FIM) score. Secondary outcomes included postoperative complication and discharge disposition. Multiple logistic regression analyses were performed using each outcome as a dependent variable and mFI as an independent variable.
Sample included 274 patients (mean age 83.7 ± 7.4 years, female 80.7%). Patients with higher mFI exhibited lower functional recovery, defined by efficiency on the motor-FIM score, and tended to run into complications and not return home (P < .001). In multiple logistic regression analyses, higher mFI was significantly associated with increased likelihood of lower functional recovery (odds ratio [OR], 1.60; 95% CI, 1.32-1.93; P < .001), occurrence of postoperative complication (OR, 1.32; 95% CI, 1.13-1.54; P < .001) and not returning home (OR, 1.77; 95% CI, 1.38-2.26; P < .001).
Frailty defined by 19-item mFI can predict short-term functional recovery during acute phase following hip fracture. Frailty is also associated with postoperative complication and discharge disposition.
许多髋部骨折患者的功能状态下降,阻碍了他们恢复到骨折前的功能状态。髋部骨折患者衰弱的患病率很高,但人们对衰弱与功能恢复的关系知之甚少。本研究旨在确定衰弱是否可以预测髋部骨折急性阶段的功能恢复和临床结局。
这是一项来自两家急性医院的回顾性观察性研究。参与者从接受手术的髋部骨折患者中招募。主要暴露因素是使用 19 项改良衰弱指数(mFI)定义的衰弱。主要结局是术后运动功能独立性测量(FIM)评分的术后效率评估的功能恢复。次要结局包括术后并发症和出院去向。使用每个结局作为因变量,mFI 作为自变量进行多因素逻辑回归分析。
样本包括 274 名患者(平均年龄 83.7±7.4 岁,女性 80.7%)。mFI 较高的患者术后功能恢复较差,表现为运动-FIM 评分效率较低,且更易发生并发症且无法回家(P<0.001)。在多因素逻辑回归分析中,较高的 mFI 与较低的功能恢复(比值比 [OR],1.60;95%置信区间 [CI],1.32-1.93;P<0.001)、术后并发症(OR,1.32;95%CI,1.13-1.54;P<0.001)和无法回家(OR,1.77;95%CI,1.38-2.26;P<0.001)的发生几率增加显著相关。
19 项 mFI 定义的衰弱可以预测髋部骨折后急性阶段的短期功能恢复。衰弱还与术后并发症和出院去向相关。