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剖宫产瘢痕处同时发生的绒毛膜癌和上皮样滋养细胞肿瘤:一例报告并文献复习

Synchronous Choriocarcinoma and Epithelioid Trophoblastic Tumor Concurring at the Cesarean Scar: A Case Report and Review of the Literature.

作者信息

Zeng Chunyan, Rezai Shadi, Hughes Alexander C, Henderson Cassandra E, Liu Juan

机构信息

Key Laboratory for Major Obstetric Diseases of Guangdong Province, Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institutes, Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Guangzhou Medical University, Duobao Road 63, Liwan District, Guangzhou, Guangdong 510150, China.

Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology, Baylor College of Medicine, 6651 Main Street, 10 Floor, Houston, TX 77030, USA.

出版信息

Case Rep Obstet Gynecol. 2019 Sep 16;2019:5093938. doi: 10.1155/2019/5093938. eCollection 2019.

Abstract

We present a complicated case of recurrence of gestational trophoblastic neoplasms (GTN), mixed ETT and choriocarcinoma at an abdominal cesarean scar. This tumor consisted of typical morphologic and immunophenotypic features of ETT and choriocarcinoma. The tumor recurred despite the patient undergoing chemotherapy. The patient had this abdominal mass resected three times. The elements of ETT and coexisting choriocarcinoma varied each time. Due to re-recurrence of the tumor, the following decisions had been made: total abdominal hysterectomy, bilateral salpingectomy, right-sided inguinal lymph node biopsy. At the time of this report, recurrence was negative.

摘要

我们报告一例复杂的妊娠滋养细胞肿瘤(GTN)复发病例,为腹部剖宫产瘢痕处混合性上皮样滋养细胞肿瘤(ETT)和绒毛膜癌。该肿瘤具有ETT和绒毛膜癌典型的形态学及免疫表型特征。尽管患者接受了化疗,肿瘤仍复发。患者接受了三次腹部肿物切除术。每次ETT成分及并存的绒毛膜癌成分均有所不同。由于肿瘤再次复发,遂决定行全腹子宫切除术、双侧输卵管切除术及右侧腹股沟淋巴结活检。在本报告之时,复查未见复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ca/6766115/f9b84dc39d43/CRIOG2019-5093938.001.jpg

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