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下颌第二磨牙Ⅱ度根分叉病变的引导组织再生:一项临床研究

Guided tissue regeneration in degree II furcation-involved mandibular molars. A clinical study.

作者信息

Pontoriero R, Lindhe J, Nyman S, Karring T, Rosenberg E, Sanavi F

机构信息

Department of Periodontology, School of Dental Medicine, University of Pennsylvania, Philadelphia.

出版信息

J Clin Periodontol. 1988 Apr;15(4):247-54. doi: 10.1111/j.1600-051x.1988.tb01578.x.

Abstract

The present clinical trial was designed to evaluate the regenerative potential of the periodontal tissues in degree II furcation defects at mandibular molars using a surgical treatment technique based on the principles of guided tissue regeneration. The patient sample included 21 subjects, 22-65 years of age. The patients selected had periodontal lesions in the right and left molar regions including advanced periodontal tissue destruction within the interradicular area. After an initial examination, each patient received a series of full-mouth scalings and root planings. 2-3 months later, they were recalled for a baseline examination including assessment of plaque, gingivitis, probing depths and probing attachment levels. The furcation involved molars were randomly assigned in each patient to either a test or a control treatment procedure. The test procedure included the elevation of mucoperiosteal flaps at the buccal and lingual aspect of the alveolar process. The inner surface of each flap was carefully curetted to remove epithelium and granulation tissue. The root surfaces were scaled and planed. A teflon membrane was adjusted to cover the entrance of the furcation area and the adjacent root surfaces as well as a portion of the alveolar bone apical to the crest. The flaps were repositioned and placed on the outer surface of the membrane and secured with interdental sutures which were removed after 10 days of healing. Following surgery, the patients were instructed to rinse the mouth twice daily with chlorhexidine gluconate. A second surgical procedure was performed after a healing period of 1-2 months to remove the teflon membrane.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

本临床试验旨在采用基于引导组织再生原理的手术治疗技术,评估下颌磨牙Ⅱ度根分叉病变牙周组织的再生潜力。患者样本包括21名年龄在22至65岁之间的受试者。入选患者双侧磨牙区均有牙周病变,包括根分叉区域严重的牙周组织破坏。初诊后,每位患者接受了一系列全口洁治和根面平整治疗。2至3个月后,患者被召回进行基线检查,包括菌斑、牙龈炎、探诊深度和探诊附着水平的评估。每位患者中,受累的根分叉磨牙被随机分配接受试验性或对照性治疗程序。试验性程序包括在牙槽突颊侧和舌侧掀起黏骨膜瓣。仔细刮除每个瓣的内表面以去除上皮和肉芽组织。对根面进行刮治和平整。调整一块聚四氟乙烯膜以覆盖根分叉区域入口、相邻根面以及嵴顶下方的部分牙槽骨。将瓣复位并放置在膜的外表面,用牙间缝线固定,愈合10天后拆除缝线。术后,指导患者每天用葡萄糖酸洗必泰漱口两次。在1至2个月的愈合期后进行第二次手术,以取出聚四氟乙烯膜。(摘要截选至250字)

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