二维斑点追踪超声心动图对冠心病患者左心房功能按血糖状态的评估
Two-dimensional speckle-tracking echocardiography evaluation of left atrial function according to glycemic state in patients with coronary artery disease.
作者信息
Hosseinsabet Ali, Mohseni-Badalabadi Reza, Jalali Arash
机构信息
Departments of Cardiology.
Research, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
出版信息
Cardiovasc Endocrinol. 2017 Aug 18;6(3):101-108. doi: 10.1097/XCE.0000000000000127. eCollection 2017 Sep.
UNLABELLED
Prediabetes and diabetes are dysglycemic conditions associated with increased cardiovascular risks and subtle myocardial injuries. The aim of our study was to evaluate left atrial (LA) function by two-dimensional speckle-tracking echocardiography in prediabetic and diabetic patients with coronary artery disease (CAD) and compare the results with those in euglycemic patients with CAD.
METHODS
The study population comprised 205 consecutive patients with CAD: 104 diabetic, 51 prediabetic, and 50 euglycemic patients. LA function was evaluated with two-dimensional speckle-tracking echocardiography and the longitudinal deformation indices of the LA were measured.
RESULTS
Our results showed that early diastolic strain was lower in the diabetic patients than in the prediabetic and euglycemic patients. The absolute value of early diastolic strain rate was reduced in the diabetic patients compared with the euglycemic patients. Late diastolic strain was increased in the diabetic patients compared with the prediabetic and euglycemic patients. The multivariate analysis showed that diabetes was a determinant of early diastolic strain and strain rate, but not late diastolic strain.
CONCLUSION
LA conduit function, as evaluated in terms of early diastolic strain and strain rate, was impaired in the diabetic CAD patients compared with the prediabetic and euglycemic CAD patients.
未标注
糖尿病前期和糖尿病是血糖异常状况，与心血管风险增加及轻微心肌损伤相关。我们研究的目的是通过二维斑点追踪超声心动图评估糖尿病前期和糖尿病合并冠状动脉疾病（CAD）患者的左心房（LA）功能，并将结果与血糖正常的CAD患者进行比较。
方法
研究人群包括205例连续的CAD患者：104例糖尿病患者、51例糖尿病前期患者和50例血糖正常的患者。采用二维斑点追踪超声心动图评估LA功能，并测量LA的纵向变形指标。
结果
我们的结果显示，糖尿病患者舒张早期应变低于糖尿病前期和血糖正常的患者。与血糖正常的患者相比，糖尿病患者舒张早期应变率的绝对值降低。与糖尿病前期和血糖正常的患者相比，糖尿病患者舒张晚期应变增加。多因素分析显示，糖尿病是舒张早期应变和应变率的决定因素，但不是舒张晚期应变的决定因素。
结论
与糖尿病前期和血糖正常的CAD患者相比，糖尿病CAD患者的LA管道功能（根据舒张早期应变和应变率评估）受损。
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