有机溶剂暴露工人的神经心理学效应。
Neuropsychological effects among workers exposed to organic solvents.
机构信息
Unidad de Investigación de Salud en el Trabajo, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social. Mexico City, Mexico.
Dirección de Investigación y Posgrado, Claustro Universitario de Chihuahua. Chihuahua, Mexico.
出版信息
Salud Publica Mex. 2019 Sep-Oct;61(5):670-677. doi: 10.21149/9800.
OBJECTIVE
To assess neuropsychological performance among workers at a paint factory in Mexico City.
MATERIALS AND METHODS
During 2004 and 2005 we assessed the neuropsychological performance of 208 workers who were exposed to organic solvents at a paint factory, mainly toluene and xylene. We categorized workers into low and high exposure groups using a cumulative index for toluene, based on times spent in different tasks. We evaluated cognitive and motor functions with 13 neuropsychological tests.
RESULTS
We found lower attention, longer time to complete the test β=5.5 (R2=12.3%), and a lower score in the motor-cognitive test β=-15.7 (R2=19.5%) in the high exposure group through multiple linear regression model analysis, with adjustment for age and education.
CONCLUSIONS
Our results are similar to the ones reported in the literature, but the effects are less severe, probably due to lower exposure to organic solvents.
目的
评估墨西哥城一家油漆厂工人的神经心理学表现。
材料和方法
2004 年至 2005 年期间，我们评估了 208 名在油漆厂接触有机溶剂（主要为甲苯和二甲苯）工人的神经心理学表现。我们使用基于不同任务时间的甲苯累积指数将工人分为低暴露组和高暴露组。我们使用 13 项神经心理学测试评估认知和运动功能。
结果
通过多元线性回归模型分析，调整年龄和教育因素后，我们发现高暴露组的注意力较低，完成测试的时间较长，β=5.5（R2=12.3%），运动认知测试的得分较低，β=-15.7（R2=19.5%）。
结论
我们的结果与文献报道的结果相似，但影响较小，可能是由于有机溶剂暴露水平较低所致。
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