来自……茎皮的咖啡酸和哌啶 - 3 - 醇衍生物。 （注：原文中“from the stem bark of.”后面缺少具体植物名称）
Caffeate and piperidine-3-ol derivatives from the stem bark of .
作者信息
Atontsa Brice Cedric K, Bitchagno Gabin Thierry M, Mpetga James D Simo, Wamba Brice Elvis N, Nayim Paul, Tchuenguem Roland T, Ndontsa Blanche L, Koagne Romeol R, Opatz Till, Kuete Victor, Tane Pierre
机构信息
Department of Chemistry, University of Dschang, Dschang, Cameroon.
Institute of Organic Chemistry, University of Mainz, Mainz, Germany.
出版信息
Nat Prod Res. 2021 Aug;35(15):2507-2514. doi: 10.1080/14786419.2019.1684278. Epub 2019 Nov 1.
A new caffeate derivative from the ethanol extract of the stem bark of DC. is described herein along with the known secondary metabolites spectaline (), -6-cassine (), 3--methyl--inositol (), monobehenin (), octyl nonadecyloate (), -sitosterol (), stigmasterol () and sitosterol 3---D-glucopyranoside (). The chemical structures were elucidated by means of various spectroscopic and spectrometric techniques. Extract and isolated compounds were devoid of inhibitory action against the herein selected bacterial strains (MICs > 256 μg/mL) but showed capacities to reduce 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical (EC < 3 μg/mL) considerably better than the "gold standard" trolox (EC 6.47 ± 0.48 μg/mL).
本文描述了一种从DC.茎皮乙醇提取物中得到的新咖啡酸衍生物，以及已知的次生代谢产物斯佩塔林（）、-6-卡西因（）、3--甲基--肌醇（）、单山嵛酸甘油酯（）、十九烷基辛酸辛酯（）、-谷甾醇（）、豆甾醇（）和谷甾醇3---D-吡喃葡萄糖苷（）。通过各种光谱和光谱技术阐明了化学结构。提取物和分离出的化合物对本文所选细菌菌株没有抑制作用（最低抑菌浓度>256μg/mL），但显示出比“金标准”曲克芦丁（EC 6.47±0.48μg/mL）更好地还原1,1-二苯基-2-苦基肼（DPPH）自由基的能力（EC<3μg/mL）。
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