横断面研究：约旦河西岸北部成年人代谢综合征及相关危险因素。
Metabolic syndrome and related risk factors among adults in the northern West Bank, a cross-sectional study.
机构信息
Faculty of Medicine and Health Sciences, Drugs and Toxicology Division, An-Najah National University, Nablus, Palestine, 00970. P.O. Box 7.
Faculty of Medicine and Health Sciences, Department of Medicine, An-Najah National University, Nablus, Palestine, 00970. P.O. Box 7.
出版信息
Int Health. 2022 Jul 1;14(4):339-345. doi: 10.1093/inthealth/ihz093.
BACKGROUND
Metabolic syndrome (MetS) is a cluster of cardiometabolic risk factors that includes central obesity, insulin resistance, dyslipidaemia and hypertension. The aim of this study was to establish the prevalence of MetS and its associated risk factors among adult Palestinians using the International Diabetes Federation definition.
METHODS
A total of 1348 subjects ages 18-65 y were recruited in a cross-sectional study that was conducted in 2018-2019 in the northern West Bank.
RESULTS
A total of 1082 subjects participated; 51.7% were men. The prevalence of MetS was high (44.9%), and higher among women (46.1%) than men (44.2%) (p<0.001). The prevalence increased significantly with increasing age and body mass index (BMI) in both genders (p<0.001). However, metabolically obese but normal weight individuals (MONW) (8.4%) were also identified, with a slight increase among women (9.4%) compared with men (7.5%) (p=0.56). MetS was more likely to be prevalent among participants with increased fasting blood sugar (5.8 times), increased triglyceride (7.4 times), increased blood pressure (4.5 times) and BMI ≥25 (19.9 times) (p<0.001). The prevalence of MetS was higher among rural (50.3%) vs urban (39.3%) residents and refugees (33.8%).
CONCLUSIONS
With increasing age and obesity, clustering of MetS components increased remarkably in both genders. Effective prevention and treatment strategies for MetS and its risk factors should be developed targeting different ages and genders.
背景
代谢综合征（MetS）是一组心血管代谢危险因素，包括中心性肥胖、胰岛素抵抗、血脂异常和高血压。本研究旨在采用国际糖尿病联合会（IDF）的定义，确定成年巴勒斯坦人代谢综合征及其相关危险因素的流行情况。
方法
本横断面研究于 2018 年至 2019 年在约旦河西岸北部进行，共纳入 1348 名年龄在 18-65 岁的受试者。
结果
共有 1082 名受试者参与研究；其中 51.7%为男性。代谢综合征的患病率较高（44.9%），女性（46.1%）高于男性（44.2%）（p<0.001）。在两性中，随着年龄和体重指数（BMI）的增加，代谢综合征的患病率显著增加（p<0.001）。然而，也发现了代谢正常但超重的个体（MONW）（8.4%），且女性（9.4%）略高于男性（7.5%）（p=0.56）。在空腹血糖升高（5.8 倍）、甘油三酯升高（7.4 倍）、血压升高（4.5 倍）和 BMI≥25（19.9 倍）的参与者中，代谢综合征的患病率更高（p<0.001）。与城市（39.3%）居民相比，农村（50.3%）和难民（33.8%）居民的代谢综合征患病率更高。
结论
在两性中，随着年龄和肥胖的增加，代谢综合征各组成部分的聚集显著增加。应针对不同年龄和性别制定有效的代谢综合征及其危险因素预防和治疗策略。
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