Hamilton-Craig Christian R, Tandon Karman, Kwan Bianca, DeBoni Karen, Burley Chris, Wesley Allan J, O'Rourke Rachael, Neill Johanne, Branch Kelley R
The Prince Charles Hospital, Brisbane, Queensland, Australia.
University of Queensland, Brisbane, Queensland, Australia.
J Med Radiat Sci. 2020 Mar;67(1):25-33. doi: 10.1002/jmrs.358. Epub 2019 Nov 6.
Coronary CT Angiography (CCTA) is a rapidly increasing technique for coronary imaging; however, it exposes patients to ionising radiation. We examined the impact of dose reduction techniques using ECG-triggering, kVp/mAs reduction and high-pitch modes on radiation exposure in a large Australian tertiary CCTA service.
Data on acquisition modes and dose exposure were prospectively collected on all CCTA scans from November 2009 to March 2014 at an Australian tertiary care centre. A dose reduction algorithm was developed using published techniques and implemented with education of medical staff, radiographers and referrers. Associations of CCTA acquisition to radiation over time were analysed with multivariate regression. Specificity in positive CCTA was assessed by correlation with invasive coronary angiography.
3333 CCTAs were analysed. Mean radiation dose decreased from 8.4 mSv to 5.3, 4.4, 3.7, 2.9 and 2.8 mSv (P < 0.001) per year. Patient characteristics were unchanged. Dose reduction strategies using ECG-triggering, kVp/mAs reduction accounted for 91% of the decrease. High-pitch scanning reduced dose by an additional 9%. Lower dose was independently related to lower kVp, heart rate, tube current modulation, BMI, prospective triggering and high-pitch mode (P < 0.01). CCTA specificity remained unchanged despite dose reduction.
Implementation of evidence-based CCTA dose reduction algorithm and staff education programme resulted in a 67% reduction in radiation exposure, while maintaining diagnostic specificity. This approach is widely applicable to clinical practice for the performance of CCTA.
冠状动脉CT血管造影(CCTA)是一种在冠状动脉成像领域迅速发展的技术;然而,它会使患者暴露于电离辐射中。我们在澳大利亚一家大型三级医疗中心的CCTA服务中,研究了使用心电图触发、千伏峰值/管电流-时间积减少和高螺距模式等剂量降低技术对辐射暴露的影响。
前瞻性收集了2009年11月至2014年3月在澳大利亚一家三级医疗中心进行的所有CCTA扫描的采集模式和剂量暴露数据。利用已发表的技术开发了一种剂量降低算法,并在对医务人员、放射技师和转诊医生进行培训后实施。通过多变量回归分析了随时间推移CCTA采集与辐射之间的关联。通过与有创冠状动脉造影的相关性评估CCTA阳性结果的特异性。
分析了3333例CCTA。平均辐射剂量每年从8.4毫希沃特降至5.3、4.4、3.7、2.9和2.8毫希沃特(P<0.001)。患者特征未发生变化。使用心电图触发、千伏峰值/管电流-时间积减少的剂量降低策略占剂量降低的91%。高螺距扫描使剂量额外降低了9%。较低剂量与较低的千伏峰值、心率、管电流调制、体重指数、前瞻性触发和高螺距模式独立相关(P<0.01)。尽管降低了剂量,但CCTA的特异性保持不变。
实施基于证据的CCTA剂量降低算法和工作人员教育计划可使辐射暴露降低67%,同时保持诊断特异性。这种方法广泛适用于CCTA临床实践。