Magni G, Fisman M, Helmes E
Department of Psychiatry, University of Western Ontario, London, Canada.
J Clin Psychiatry. 1988 Oct;49(10):405-7.
Clinical findings in a group of 11 patients who failed to respond to at least one course of antidepressant (usually tricylic) treatment and at least seven bilateral electroconvulsive treatments (ECTs) were compared with the findings in a group of 19 patients with similar sociodemographic characteristics who were responsive to ECT. The major correlates of ECT nonresponse were onset of physical illness during the index episode, fewer life events preceding the onset of the index episode, and a higher frequency of preceding depressive episodes of longer duration in the nonresponder group.
将一组11例对至少一个疗程的抗抑郁药（通常为三环类）治疗以及至少七次双侧电休克治疗（ECT）均无反应的患者的临床发现，与一组19例具有相似社会人口统计学特征且对ECT有反应的患者的发现进行了比较。ECT无反应的主要相关因素为在本次发作期间出现躯体疾病、本次发作前的生活事件较少，以及无反应组中既往抑郁发作持续时间较长的发作频率较高。
