基于环境光传感器的比色条带读取器，可用于在智能手机上快速监测有机磷农药。
Ambient light sensor based colorimetric dipstick reader for rapid monitoring organophosphate pesticides on a smart phone.
机构信息
Department of Bioengineering, Guangdong Province Engineering Research Center for Antibody Drug and Immunoassay, Jinan University, Guangzhou, 510632, PR China; Department of Stomatology, The First Affiliated Hospital, Jinan University, Guangzhou, 510632, PR China; School of Mechanical and Materials Engineering, Washington State University, Pullman, WA, 99164, USA.
Department of Stomatology, The First Affiliated Hospital, Jinan University, Guangzhou, 510632, PR China.
出版信息
Anal Chim Acta. 2019 Dec 27;1092:126-131. doi: 10.1016/j.aca.2019.09.059. Epub 2019 Sep 26.
Organophosphate pesticides (OPs) are widely used around the world to control pests in agricultural, residential, and commercial settings. Ingestion of high-dose OPs could lead to acute toxicity, and persistent influence on health could result from acute poisoning or long-term exposure to low dose OPs. An easy to operate, low cost and home available OPs testing platform is urgently needed. Ambient light sensor (ALS) based smart phone colorimetric reader has the advantages of easy to operate, low cost, high accuracy and versatility. In this work, a novel ALS based smart phone colorimetric dipsticks (CDs) reader was reported for rapid monitoring OPs. In this method, acetylcholinesterase (ACHE) CDs was used to test OPs and results were analyzed using an ALS based reader according to the absorbance of ACHE CDs. The results obtained using the ALS based CDs reader were comparable to those obtained using gas chromatography-mass spectrometry (GC-MS) and Ellman assay. The ALS based CDs reader has the advantages of portable, low cost, and high accuracy, and therefore could act an effective platform for OPs monitoring.
有机磷农药（OPs）在世界范围内被广泛用于农业、住宅和商业环境中控制害虫。摄入高剂量的 OPs 可能导致急性毒性，而急性中毒或长期接触低剂量 OPs 则可能对健康产生持久影响。因此，我们迫切需要一种易于操作、成本低廉且可在家庭中使用的 OPs 检测平台。基于环境光传感器（ALS）的智能手机比色读取器具有易于操作、成本低、精度高和多功能等优点。在这项工作中，我们报道了一种基于 ALS 的智能手机比色试纸（CDs）读取器，用于快速监测 OPs。在该方法中，使用乙酰胆碱酯酶（ACHE）CDs 来测试 OPs，并根据 ACHE CDs 的吸光度，使用基于 ALS 的读取器进行分析。基于 ALS 的 CDs 读取器的结果与气相色谱-质谱联用（GC-MS）和 Ellman 测定法的结果相当。基于 ALS 的 CDs 读取器具有便携、低成本和高精度的优点，因此可以作为 OPs 监测的有效平台。
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