Incidence Rate and Predictors of Globus Pallidus Necrosis after Charcoal Burning Suicide.

: This study examined predictors of globus pallidus necrosis as there was a paucity of literature of globus pallidus necrosis resulted from carbon monoxide poisoning after charcoal burning suicide. : A total of 67 patients who had attempted charcoal burning suicide were recruited and stratified into two subgroups based on either presence ( = 40) or absence ( = 27) of globus pallidus necrosis. Demographic, clinical, laboratory, and radiographic data were obtained for cross-sectional analysis. All patients were followed to investigate the risks for mortality. : The patients aged 36.8 ± 11.1 years (67.2%) were male. Patients with globus pallidus necrosis were younger ( = 0.044) and had less hypertension ( = 0.015) than patients without globus pallidus necrosis. Furthermore, patients with globus pallidus necrosis suffered from severer medical complications, i.e., fever ( = 0.008), acute myocardial injury ( = 0.022), acute rhabdomyolysis ( = 0.022), and neuropsychiatric symptoms ( < 0.001) than patients without globus pallidus necrosis. Moreover, patients with globus pallidus necrosis received less hyperbaric oxygen therapy than without necrosis ( = 0.024). Two patients (3.0%) died on arrival. In a multivariable regression model, it was revealed that acute myocardial injury (odds ratio 4.6, confidence interval 1.1-18.9, = 0.034) and neuropsychiatric symptoms (odds ratio 8.0, confidence interval 2.0-31.4, = 0.003), decreased blood bicarbonate level (odds ratio 0.8, confidence interval 0.7-1.0, = 0.032), and younger age (odds ratio 0.9, confidence interval 0.9-1.0, = 0.038) were significant predictors for globus pallidus necrosis. : Although patients who had attempted charcoal burning suicide had a low mortality rate (3.0%), globus pallidus necrosis was not uncommon (59.7%) in this population. Further studies are warranted.