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内固定与关节成形术治疗老年无移位股骨颈骨折的系统评价和荟萃分析

Internal Fixation Versus Arthroplasty for the Treatment of Nondisplaced Femoral Neck Fractures in the Elderly: A Systematic Review and Meta-Analysis.

作者信息

Richards John T, Overmann Archie L, O'Hara Nathan N, D'Alleyrand Jean-Claude, Slobogean Gerard P

机构信息

Department of Orthopaedic Surgery, Uniformed Services University-Walter Reed Department of Surgery, Walter Reed National Military Medical Center, Bethesda, MD; and.

Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD.

出版信息

J Orthop Trauma. 2020 Jan;34(1):42-48. doi: 10.1097/BOT.0000000000001656.

Abstract

OBJECTIVE

To compare the outcomes of elderly patients with nondisplaced and minimally displaced femoral neck fractures treated with internal fixation versus arthroplasty.

DATA SOURCES

A comprehensive search of the MEDLINE, Embase, and central databases was conducted through June 25, 2019.

STUDY SELECTION

Studies were included if the sample population was (1) 60 years of age or older, (2) had nondisplaced or minimally displaced (Garden I or II) femoral neck fractures, and (3) if the study compared internal fixation versus arthroplasty. Only full-text English manuscripts were included. The primary outcome was reoperation. Secondary outcomes included mortality, patient-reported outcomes, length of hospital stay, infection, and blood transfusions.

DATA EXTRACTION

Two authors independently extracted data from the included studies. Each study was independently evaluated for quality using the Cochrane risk of bias assessment.

DATA SYNTHESIS

Of the 1597 identified articles, 4 manuscripts met the eligibility criteria with a total of 579 patients (236 treated with hemiarthroplasty and 343 treated with internal fixation). Patients treated with arthroplasty had a significantly lower risk of reoperation when compared with those treated with internal fixation [relative risk: 0.30 (95% CI, 0.16-0.55, P < 0.01)]. There was no significant difference detected in 1-year mortality risk between the 2 treatment groups.

CONCLUSIONS

In elderly patients with nondisplaced and minimally displaced femoral neck fractures, treatment with hemiarthroplasty may reduce the relative risk of reoperation by 70% when compared with internal fixation.

LEVEL OF EVIDENCE

Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

摘要

目的

比较老年无移位和轻度移位股骨颈骨折患者行内固定术与关节置换术的治疗效果。

数据来源

截至2019年6月25日,对MEDLINE、Embase和中央数据库进行了全面检索。

研究选择

纳入的研究需满足以下条件:(1)样本人群年龄在60岁及以上;(2)患有无移位或轻度移位(Garden I或II型)股骨颈骨折;(3)研究比较了内固定术与关节置换术。仅纳入英文全文手稿。主要结局为再次手术。次要结局包括死亡率、患者报告的结局、住院时间、感染和输血情况。

数据提取

两位作者独立从纳入的研究中提取数据。每项研究均使用Cochrane偏倚风险评估独立评估质量。

数据综合

在1597篇已识别的文章中,4篇手稿符合纳入标准,共579例患者(236例行半髋关节置换术,343例行内固定术)。与接受内固定术的患者相比,接受关节置换术的患者再次手术风险显著更低[相对风险:0.30(95%CI,0.16 - 0.55,P < 0.01)]。两个治疗组之间1年死亡率风险未检测到显著差异。

结论

在老年无移位和轻度移位股骨颈骨折患者中,与内固定术相比,半髋关节置换术治疗可使再次手术的相对风险降低70%。

证据级别

治疗性III级。有关证据级别的完整描述,请参阅作者指南。

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