GTDB-Tk：一个使用基因组分类数据库对基因组进行分类的工具包。
GTDB-Tk: a toolkit to classify genomes with the Genome Taxonomy Database.
作者信息
Chaumeil Pierre-Alain, Mussig Aaron J, Hugenholtz Philip, Parks Donovan H
机构信息
Australian Centre for Ecogenomics, School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.
出版信息
Bioinformatics. 2019 Nov 15;36(6):1925-7. doi: 10.1093/bioinformatics/btz848.
SUMMARY
The GTDB Toolkit (GTDB-Tk) provides objective taxonomic assignments for bacterial and archaeal genomes based on the Genome Taxonomy Database (GTDB). GTDB-Tk is computationally efficient and able to classify thousands of draft genomes in parallel. Here we demonstrate the accuracy of the GTDB-Tk taxonomic assignments by evaluating its performance on a phylogenetically diverse set of 10,156 bacterial and archaeal metagenome-assembled genomes.
AVAILABILITY
GTDB-Tk is implemented in Python and licensed under the GNU General Public License v3.0. Source code and documentation are available at: https://github.com/ecogenomics/gtdbtk.
SUPPLEMENTARY INFORMATION
Supplementary data are available at Bioinformatics online.
摘要
GTDB工具包（GTDB-Tk）基于基因组分类数据库（GTDB）为细菌和古菌基因组提供客观的分类学归属。GTDB-Tk计算效率高，能够并行分类数千个草图基因组。在这里，我们通过评估GTDB-Tk在10156个细菌和古菌宏基因组组装基因组的系统发育多样集合上的性能，证明了其分类学归属的准确性。
可用性
GTDB-Tk用Python实现，并根据GNU通用公共许可证v3.0授权。源代码和文档可在以下网址获取：https://github.com/ecogenomics/gtdbtk。
补充信息
补充数据可在《生物信息学》在线获取。
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