可溶性髓系细胞触发受体-1：诊断还是预后？
Soluble Triggering Receptor Expressed on Myeloid Cells-1: Diagnosis or Prognosis?
机构信息
CHRU Nancy, Hôpital Central, Service de Réanimation Médicale, 29 avenue de LAttre de Tassigny, 54000 Nancy, France; INSERM UMRS-1116, Faculté de Médecine Nancy, Université de Lorraine, 9 avenue de la forêt de Haye, 54500 Vandoeuvre-les-Nancy, France.
CHRU Nancy, Hôpital Central, Service de Réanimation Médicale, 29 avenue de LAttre de Tassigny, 54000 Nancy, France; INSERM UMRS-1116, Faculté de Médecine Nancy, Université de Lorraine, 9 avenue de la forêt de Haye, 54500 Vandoeuvre-les-Nancy, France.
出版信息
Crit Care Clin. 2020 Jan;36(1):41-54. doi: 10.1016/j.ccc.2019.08.004. Epub 2019 Oct 18.
The diagnosis of sepsis, and especially its differentiation from sterile inflammation, may be challenging. The triggering receptor expressed on myeloid cells-1 is an amplifier of the innate immune response. Its soluble form is detectable in various biological fluids and can be used as a surrogate marker of triggering receptor expressed on myeloid cells-1 activation. In this article, we review the abundant literature evaluating the usefulness of soluble triggering receptor expressed on myeloid cells-1 for the diagnosis and the prognosis evaluation of sepsis or localized infections.
脓毒症的诊断，尤其是将其与无菌性炎症区分开来，可能具有挑战性。髓系细胞表达的触发受体-1是先天免疫反应的放大器。其可溶性形式可在各种生物液中检测到，并可用作触发受体-1 激活的替代标志物。本文综述了大量文献，评估了可溶性髓系细胞表达的触发受体-1在脓毒症或局部感染的诊断和预后评估中的作用。
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