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空肠穿孔并发皮肌炎

Jejunal perforation complicating dermatomyositis.

作者信息

Lee Donghyoun, Jeong Woo Seong, Hyun Chang Lim, Kim Jinseok

机构信息

Department of Surgery, Jeju National University Hospital, Jeju National University School of Medicine, Jeju Self-governing Province, South Korea.

Division of Rheumatology, Department of Internal Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju Self-governing Province, South Korea.

出版信息

Int J Surg Case Rep. 2019;65:245-248. doi: 10.1016/j.ijscr.2019.04.010. Epub 2019 Apr 10.

Abstract

INTRODUCTION

Small bowel perforation is rare in dermatomyositis (DM). However, it is associated with high rates of morbidity and mortality. In line with the SCARE criteria, we describe a case of jejunal perforation for a DM patient (Agha et al., 2018 [1]).

CASE PRESENTATION

A 63-year-old woman had been treated for DM with high dose steroid 1 month prior to the onset of severe abdominal pain. Computed tomography (CT) revealed free air in abdominal cavity and fluid around the small bowel. She was diagnosed with small bowel perforation and underwent emergency surgery. Emergent surgery showed perforated jejunum which was resected. Pathologic reports revealed mesenteric small-vessel vasculitis with a perivascular inflammatory cell infiltration.

CONCLUSION

Perforation of the small bowel for DM patients is rare. However, the early diagnosis of bowel perforation is difficult in DM because it can mimic other gastrointestinal manifestations such as ileus, ischemic colitis and peritonitis. To minimize mortality via an early diagnosis and a timely treatment, it is important to examine the patient's clinical history and employ a proper medical imaging modality such as CT even when lab findings are nonspecific and atypical.

摘要

引言

小肠穿孔在皮肌炎(DM)中较为罕见。然而,其与高发病率和死亡率相关。根据SCARE标准,我们描述一例皮肌炎患者空肠穿孔的病例(Agha等人,2018 [1])。

病例介绍

一名63岁女性在出现严重腹痛前1个月接受了高剂量类固醇治疗皮肌炎。计算机断层扫描(CT)显示腹腔内有游离气体和小肠周围有液体。她被诊断为小肠穿孔并接受了急诊手术。急诊手术显示空肠穿孔并进行了切除。病理报告显示肠系膜小血管血管炎伴血管周围炎性细胞浸润。

结论

皮肌炎患者小肠穿孔罕见。然而,皮肌炎中肠穿孔的早期诊断困难,因为它可模仿其他胃肠道表现,如肠梗阻、缺血性结肠炎和腹膜炎。为通过早期诊断和及时治疗将死亡率降至最低,即使实验室检查结果不特异且不典型,检查患者的临床病史并采用适当的医学成像方式(如CT)也很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5899/6864317/6bf8cae68009/gr1.jpg

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