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烟囱技术治疗主动脉弓部病变的结果:单中心 226 例经验。

Outcomes Of Chimney Technique For Aortic Arch Diseases: A Single-Center Experience With 226 Cases.

机构信息

Institute of Cardiovascular Disease and Key Laboratory for Arteriosclerology of Hunan Province, Hengyang Medical School, University of South China, Hengyang, Hunan, People's Republic of China.

Department of Cardiology, Vascular Center, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, People's Republic of China.

出版信息

Clin Interv Aging. 2019 Oct 25;14:1829-1840. doi: 10.2147/CIA.S222948. eCollection 2019.

Abstract

PURPOSE

The goal of present study is to document our single-center experience with chimney technique for aortic arch diseases.

PATIENTS AND METHODS

From August 2012 to October 2017, 226 patients (mean age 54±12 years; 197 men) with aortic arch diseases underwent thoracic endovascular aortic repair combined with chimney stents. The aortic stent-grafts were deployed in zone 0 (n=22), zone 1 (n=13), or zone 2 (n=191).

RESULTS

The technical success rate was 84% (189/226) and immediate type Ia endoleak (ELIa) happened in 37 (16%) patients. The 30-day mortality and morbidity rates were 2% (4/226) and 4% (8/226), respectively. Major adverse events include four major strokes, three spinal cord ischemia and one aortic rupture in the early-term. The clinical and imaging follow-up rates were 98% (218/222) and 78% (173/222), respectively. The average lengths of clinical and imaging follow-up were 22±16 months and 20±15 months, respectively. Chimney stent obstructions in left subclavian arteries were recorded in six (3%) patients. During follow-up, five patients died (2%) and two major strokes occurred (1%). One patient (0.5%) underwent reintervention.

CONCLUSION

The current study documented that the chimney technique is effective and safe for treating aortic arch diseases in different aortic zones. Cautions are needed to assess the permanency of chimney stent and to reduce the immediate ELIa rate.

摘要

目的

本研究旨在记录我们在主动脉弓疾病中使用烟囱技术的单中心经验。

患者与方法

2012 年 8 月至 2017 年 10 月,226 例主动脉弓疾病患者(平均年龄 54±12 岁;男性 197 例)接受了胸主动脉腔内修复术联合烟囱支架治疗。主动脉支架移植物在 0 区(n=22)、1 区(n=13)或 2 区(n=191)植入。

结果

技术成功率为 84%(189/226),37 例(16%)发生即时型 Ia 内漏(ELIa)。30 天死亡率和发病率分别为 2%(4/226)和 4%(8/226)。主要不良事件包括早期 4 例大中风、3 例脊髓缺血和 1 例主动脉破裂。临床和影像学随访率分别为 98%(218/222)和 78%(173/222)。平均临床和影像学随访时间分别为 22±16 个月和 20±15 个月。6 例(3%)患者左锁骨下动脉出现烟囱支架阻塞。随访期间,5 例患者死亡(2%),2 例发生大中风(1%)。1 例患者(0.5%)接受了再次介入治疗。

结论

本研究证明了烟囱技术在治疗不同主动脉区域的主动脉弓疾病方面是有效和安全的。需要注意评估烟囱支架的永久性,并降低即时型 ELIa 发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ad/6818674/a6fbb97a96dd/CIA-14-1829-g0001.jpg

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