Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Department of Pediatrics, College of Medicine, University of Florida, PO Box 100296, Gainesville, FL, 32610, USA.
BMC Pediatr. 2019 Nov 21;19(1):450. doi: 10.1186/s12887-019-1828-5.
Herpetic whitlow is a viral infection caused by the herpes simplex virus (HSV) types 1 or 2, and occurs in the pediatric population primarily on the fingers and toes due to autoinoculation from oral secretions. Because of this cited prevalence, other locations of herpetic whitlow may go unrecognized.
We present an atypical presentation of palmar herpetic whitlow with delayed recognition and associated viral lymphangitis. The patient presented as a transfer from an outside hospital with a progressive, three-day history of a suspected left hand abscess preceded by left hand pain and itching. She was initially evaluated by Orthopedic Surgery, who described an erythematous, edematous, tender, left palmar abscess with associated erythematous streaking up her forearm. The lesion was surgically managed with an incision and drainage. Wound cultures were obtained during which "minimal drainage" was noted. After admission to the General Pediatrics Hospital service, the lesion was noted to appear vesicular and subsequently obtained PCR samples were positive for HSV type 1, confirming her diagnosis of herpetic whitlow. Although she remained afebrile with negative wound cultures throughout her hospitalization, a secondary bacterial infection could not be conclusively excluded due to the accompanying lymphangitis. Thus, she was discharged with oral antibiotics and anticipatory guidance of potential recurrence of palmar lesions.
Herpetic whitlow should be included in the differential diagnosis of palmar lesions that appear vesicular or abscess-like to ensure appropriate treatment. Additionally, these palmar lesions may present with associated lymphangitis without evidence of bacterial infection.
疱疹性瘭疽是由单纯疱疹病毒(HSV)1 型或 2 型引起的病毒感染,主要发生在儿童手指和脚趾,由于来自口腔分泌物的自身接种而发生。由于这种流行率,疱疹性瘭疽的其他部位可能未被识别。
我们介绍了一种不典型的手掌疱疹性瘭疽表现,具有延迟识别和相关的病毒性淋巴管炎。该患者因疑似左手脓肿进行了为期三天的渐进性左手疼痛和瘙痒病史而从外院转入。她最初由矫形外科评估,描述了一个红斑、水肿、触痛的左手掌脓肿,伴有红斑性条纹向上臂延伸。该病变通过切开和引流进行了手术处理。在获得伤口培养物期间,注意到“少量引流”。入住普通儿科医院服务后,注意到病变呈水疱状,随后获得的 PCR 样本对 1 型单纯疱疹病毒呈阳性,确诊为疱疹性瘭疽。尽管她在整个住院期间均无发热且伤口培养物为阴性,但由于伴随的淋巴管炎,无法明确排除继发细菌感染的可能性。因此,她出院时口服抗生素,并对手掌病变的潜在复发进行了预期指导。
应将疱疹性瘭疽纳入手掌病变的鉴别诊断,这些病变表现为水疱状或脓肿样,以确保进行适当的治疗。此外,这些手掌病变可能出现伴有淋巴管炎而无细菌感染证据。