一种源自马里亚纳海沟的放线菌属菌株HDN 17 - 237产生的新代谢产物。
New metabolites from a Mariana Trench-derived actinomycete sp. HDN 17-237.
作者信息
Wang Jun-Xiao, Sun Chun-Xiao, Shah Mudassir, Zhang Guo-Jian, Gu Qian-Qun, Zhu Tian-Jiao, Che Qian, Li De-Hai
机构信息
School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China.
出版信息
J Asian Nat Prod Res. 2020 Nov;22(11):1031-1036. doi: 10.1080/10286020.2019.1681411. Epub 2019 Nov 22.
One new ,-butenoate derivative phenylbutenote (), and one new -pyrone nocapyrone T () were isolated from the deep-sea derived actinomycete sp. HDN 17-237. Their structures were elucidated by extensive HRMS, IR and NMR analyses. Among them, compound is the first microbial natural products bearing a rare ,-butenoate moiety, and compound is the first pyrone isolated from strain of Mariana Trench. Compounds and were tested for antioxidant and antibacterial activities, while none of them showed significant activity.
从深海来源的放线菌HDN 17-237中分离出一种新的丁烯酸酯衍生物苯基丁烯酸酯（）和一种新的吡喃酮诺卡吡喃酮T（）。通过广泛的高分辨质谱、红外光谱和核磁共振分析对它们的结构进行了阐明。其中，化合物是首个带有罕见丁烯酸酯部分的微生物天然产物，化合物是从马里亚纳海沟菌株中分离出的首个吡喃酮。对化合物和进行了抗氧化和抗菌活性测试，但它们均未表现出显著活性。
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