High-resolution performance of triptycene functionalized with polycaprolactones for gas chromatography.

Developing highly selective stationary phases is essential to address the issues for separation of analytes with similar properties and various components in complex samples. Herein, we report a new triptycene-based material functionalized with polycaprolactone moieties (TP-PCL) as the stationary phase with high-resolution performance for gas chromatography (GC). The TP-PCL capillary column exhibited column efficiency of 5555 plates/m and moderate polarity. On the column, dozens of mixtures of positional and structural isomers can be well resolved, involving benzene derivatives with varying substituents (alkyl, halo, nitro, hydroxyl, amino), naphthalene derivatives, alkanes and alcohols. It exhibits advantageous performance for high resolution of the critical pairs of alkylbenzenes, phenols, anilines and alkanes over the PCL column and commercial DB-35 MS column with similar polarity. Moreover, the TP-PCL column showed excellent separation repeatability and reproducibility with RSD values of 0.02%-0.07% for run-to-run (n = 4), 0.11%-0.18% for day-to-day (n = 4) and 2.1%-4.7% for column-to-column (n = 4). In addition, it exhibited distinctly enhanced thermal stability in contrast to the PCL column. Its application to analysis of the essential oil from Artemisiae argyi proves its good potential for practical use.