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为旁观者目睹的院外心脏骤停患者增加配备医师的救护车的益处:一项在日本新潟进行的基于社区的观察性研究。

Benefits of adding a physician-staffed ambulance to bystander-witnessed out-of-hospital cardiac arrest: a community-based, observational study in Niigata, Japan.

作者信息

Sato Nobuhiro, Matsuyama Tasuku, Akazawa Kohei, Nakazawa Kyoko, Hirose Yasuo

机构信息

Department of Emergency and Critical Care Medicine, Niigata City General Hospital, Niigata, Japan

Department of Emergency Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.

出版信息

BMJ Open. 2019 Nov 26;9(11):e032967. doi: 10.1136/bmjopen-2019-032967.

Abstract

OBJECTIVE

This study aimed to assess the benefits of adding a physician-staffed ambulance to bystander-witnessed out-of-hospital cardiac arrest using a community-based registry.

DESIGN

Population-based, retrospective cohort study.

SETTING

An urban city with approximately 800 000 residents.

PARTICIPANTS

Patients aged ≥18 years with bystander-witnessed out-of-hospital cardiac arrests of medical aetiology in Niigata City, Japan, between January 2012 and December 2016, according to the Utstein style.

PRIMARY AND SECONDARY OUTCOME MEASURES

The primary outcome was 1-month survival with a favourable neurological outcome, defined as a cerebral performance category score of 1 or 2. We used logistic regression analysis to assess the association between favourable neurological outcome and prehospital physician involvement.

RESULTS

During the study period, a total of 4172 cardiac arrests were registered; of these, 892 patients with out-of-hospital cardiac arrest were eligible for this analysis, among whom 135 (15.1%) had prehospital physician involvement and 757 (84.9%) did not have prehospital physician involvement. The percentage of favourable neurological outcomes was 20.7% (28 of 135) in those with physician involvement and 10.4% (79 of 757) in those without physician involvement (p=0.001). Using multivariable logistic regression, prehospital physician involvement had an OR for a favourable neurological outcome of 3.44 (95% CI 1.64 to 7.23).

CONCLUSIONS

Among adults with out-of-hospital cardiac arrest, adding a physician-staffed ambulance was associated with significantly greater favourable neurological outcomes than standard emergency medical services.

摘要

目的

本研究旨在通过社区登记系统评估在旁观者目击的院外心脏骤停患者中增加配备医师的救护车所带来的益处。

设计

基于人群的回顾性队列研究。

地点

一个拥有约80万居民的城市。

参与者

根据乌斯坦模式,2012年1月至2016年12月期间,日本新潟市年龄≥18岁、由旁观者目击的病因是医学因素的院外心脏骤停患者。

主要和次要结局指标

主要结局是1个月存活且神经功能良好,定义为脑功能分类评分为1或2。我们使用逻辑回归分析来评估神经功能良好与院前医师参与之间的关联。

结果

在研究期间,共登记了4172例心脏骤停;其中,892例院外心脏骤停患者符合本分析条件,其中135例(15.1%)有院前医师参与,757例(84.9%)没有院前医师参与。有医师参与的患者中神经功能良好的比例为20.7%(135例中的28例),没有医师参与的患者中这一比例为10.4%(757例中的79例)(p = 0.001)。使用多变量逻辑回归分析,院前医师参与使神经功能良好的比值比为3.44(95%可信区间为1.64至7.23)。

结论

在院外心脏骤停的成年人中,增加配备医师的救护车与比标准紧急医疗服务显著更高的良好神经功能结局相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f592/6887019/56a5a219bdd2/bmjopen-2019-032967f01.jpg

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