亚砷酸盐的长期治疗通过上调人尿路上皮细胞系中的表皮生长因子（EGF）、转化生长因子α（TGFα）和热休克蛋白90（HSP90）来激活HER1和HER2。 - Suppr

Long-term treatment with arsenite activates HER1 and HER2 through upregulating EGF, TGFα, and HSP90 in a human uroepithelial cell line.

作者信息

Jin Peiyu, Liu Jieyu, Zhou Qing, Li Sihao, Liu Weijue, Xi Shuhua

机构信息

Department of Occupational and Environmental Health, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, 110122, Shenyang, People's Republic of China.

出版信息

Cell Biol Toxicol. 2020 Jun;36(3):279-284. doi: 10.1007/s10565-019-09500-9. Epub 2019 Nov 26.

DOI:10.1007/s10565-019-09500-9

PMID:31773452

Abstract

摘要

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Long-term treatment with arsenite activates HER1 and HER2 through upregulating EGF, TGFα, and HSP90 in a human uroepithelial cell line.

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