Carvajal Daniela, Quiroz Claudia, Morales Claudia, Fernández Javier
Dermatology Department, Faculty of Medicine, University of Chile, Santiago, Chile.
Dermatology Unit, Clinical Hospital University of Chile, Santiago, Chile.
An Bras Dermatol. 2019 Sep-Oct;94(5):582-585. doi: 10.1016/j.abd.2019.09.002. Epub 2019 Sep 30.
Granulomatous pigmented purpuric dermatosis clinically manifests as hyperpigmented maculae and petechiae, predominantly on the lower extremities. Histopathologically, it is characterized by a lymphocytic infiltrate in the upper dermis, extravasated erythrocytes, and hemosiderin deposits. There is an infrequent variant called granulomatous pigmented purpuric dermatosis, which histologically is characterized by the presence of non-necrotizing granulomas associated with the classic findings of other pigmented purpuric dermatoses. It more frequently affects middle-aged women of Asian origin, and predominantly on the lower extremities. The authors present the case of a female patient with granulomatous pigmented purpuric dermatosis on the lower extremities with blaschkoid distribution.
肉芽肿性色素性紫癜性皮病临床表现为色素沉着斑和瘀点,主要见于下肢。组织病理学上,其特征为真皮上层淋巴细胞浸润、红细胞外渗和含铁血黄素沉积。有一种罕见的变异型称为肉芽肿性色素性紫癜性皮病,组织学上其特征为存在非坏死性肉芽肿,并伴有其他色素性紫癜性皮病的典型表现。它更常见于亚洲裔中年女性,且主要累及下肢。作者报告了一例下肢出现线状分布的肉芽肿性色素性紫癜性皮病的女性患者。