Tomita Tetsu, Kudo Shuhei, Sugawara Norio, Fujii Akira, Tsuruga Koji, Sato Yasushi, Ishioka Masamichi, Nakamura Kazuhiko, Yasui-Furukori Norio
Department of Neuropsychiatry, Graduate School of Medicine, Hirosaki University, Hirosaki, Japan.
Department of Psychiatry, Tsugaru General Hospital, Goshogawara, Japan.
Neuropsychiatr Dis Treat. 2019 Nov 6;15:3069-3078. doi: 10.2147/NDT.S207544. eCollection 2019.
We aimed to reveal sex differences in depression comprehension by reanalyzing data from a previous study of patients who were administered antidepressants.
A total of 424 outpatients were enrolled in the study. Participants were provided an original self-administered questionnaire that comprised eight items: depressive symptoms, course of depression, cause of depression, treatment plan, duration of antidepressant use, how to discontinue antidepressants, side effects of antidepressants, and psychotherapy. Each item consisted of the following two questions: "Have you received an explanation from the doctor in charge?" and "How much do you understand about your treatment?" The level of patients' comprehension of these questions was rated on a scale of 0-10 (11 anchor points). Symptoms were evaluated using the Quick Inventory for Depressive Symptomatology, Japanese version, and other scales. Patients were divided on the basis of sex, regardless of whether they were in remission.
Compared with male patients, female patients with depression exhibited lower levels of depression and did not receive adequate psychoeducation from their physicians. While depression comprehension of female patients might not necessarily be associated with remission, male patients in remission received more explanations about depression and understood more compared with female patients.
Depression comprehension of male patients might be associated with remission, and psychoeducation should be sex-oriented to improve treatment responses.
我们旨在通过重新分析之前一项针对服用抗抑郁药患者的研究数据，揭示抑郁症认知方面的性别差异。
本研究共纳入424名门诊患者。参与者被提供一份原始的自填问卷，该问卷包含八个项目：抑郁症状、抑郁病程、抑郁原因、治疗方案、抗抑郁药使用时长、如何停用抗抑郁药、抗抑郁药的副作用以及心理治疗。每个项目由以下两个问题组成：“您是否从主治医生那里得到了解释？”以及“您对自己的治疗了解多少？”患者对这些问题的理解程度以0至10分（11个锚点）进行评分。症状使用《抑郁症状快速检查表》日语版和其他量表进行评估。患者按性别划分，无论其是否处于缓解期。
与男性患者相比，患有抑郁症的女性患者抑郁程度较低，且未从医生那里得到充分的心身医学教育。虽然女性患者对抑郁症的认知不一定与缓解有关，但处于缓解期的男性患者比女性患者得到了更多关于抑郁症的解释且理解得更多。
男性患者对抑郁症的认知可能与缓解有关，心身医学教育应根据性别进行调整以改善治疗反应。
