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中线剖腹手术后采用腹直肌鞘阻滞(RSB)镇痛的简明疼痛量表(BPI)健康调查:癌症和良性疾病患者的随机试验。

Brief Pain Inventory (BPI) Health Survey After Midline Laparotomy With the Rectus Sheath Block (RSB) Analgesia: A Randomised Trial of Patients With Cancer and Benign Disease.

机构信息

Department of Surgery, Kuopio University Hospital and School of Medicine, University of Eastern Finland, Kuopio, Finland.

Science Service Center, Kuopio University Hospital, Kuopio, Finland.

出版信息

Anticancer Res. 2019 Dec;39(12):6751-6757. doi: 10.21873/anticanres.13890.

Abstract

BACKGROUND/AIM: Our original hypothesis was that the rectus sheath block (RSB) analgesia could enhance patient satisfaction and decrease pain following midline laparotomy.

PATIENTS AND METHODS

Initially, 56 patients were randomized into four groups; control group (n=12), single-dose (n=16), repeated-dose (n=12) and continuous infusion (n=16) RSB analgesia groups. The BPI (Brief Pain Inventory) survey was conducted preoperatively and at one and four weeks and 12 months postoperatively. The patients pain 24 h postoperatively and satisfaction 48 h postoperatively was filled on an 11-point numeric rating scale (NRS).

RESULTS

The repeated-dose group had lower BPI severity score (p=0.045) and BPI interference score (p=0.043) mean values postoperatively compared to the three other groups separately. Also, the time effect on the linear mixed model in BPI interference score mean values was statistically significant (p=0.008), which means that in the repeated dose group preoperative BPI severity score [2.7 (3.9)] and interference score [4.3 (4.2)] mean (SD) values were significantly higher than the BPI severity score [1.3 (0.8)] and interference score [1.5 (1.8)] mean (SD) values following surgery.

CONCLUSION

The higher elevation in BPI severity score and decrease in interference score values in the repeated dose group and also the time effect in a linear mixed model in BPI interference score were statistically significant.

摘要

背景/目的:我们最初的假设是腹直肌鞘阻滞(RSB)镇痛可以提高患者满意度并减轻经腹正中切口手术后的疼痛。

患者和方法

最初,56 名患者被随机分为四组:对照组(n=12)、单次剂量组(n=16)、重复剂量组(n=12)和连续输注组(n=16)。在术前、术后 1 周、4 周和 12 个月进行 BPI(简明疼痛量表)调查。术后 24 小时的疼痛和 48 小时的满意度通过 11 点数字评分量表(NRS)进行评估。

结果

与其他三组相比,重复剂量组术后 BPI 严重程度评分(p=0.045)和 BPI 干扰评分(p=0.043)平均值较低。此外,线性混合模型中 BPI 干扰评分平均值的时间效应具有统计学意义(p=0.008),这意味着在重复剂量组中,术前 BPI 严重程度评分[2.7(3.9)]和干扰评分[4.3(4.2)]的平均值明显高于术后的 BPI 严重程度评分[1.3(0.8)]和干扰评分[1.5(1.8)]。

结论

重复剂量组的 BPI 严重程度评分升高和干扰评分降低以及 BPI 干扰评分线性混合模型中的时间效应具有统计学意义。

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