Department of Surgery, Kuopio University Hospital and School of Medicine, University of Eastern Finland, Kuopio, Finland.
Science Service Center, Kuopio University Hospital, Kuopio, Finland.
Anticancer Res. 2019 Dec;39(12):6751-6757. doi: 10.21873/anticanres.13890.
BACKGROUND/AIM: Our original hypothesis was that the rectus sheath block (RSB) analgesia could enhance patient satisfaction and decrease pain following midline laparotomy.
Initially, 56 patients were randomized into four groups; control group (n=12), single-dose (n=16), repeated-dose (n=12) and continuous infusion (n=16) RSB analgesia groups. The BPI (Brief Pain Inventory) survey was conducted preoperatively and at one and four weeks and 12 months postoperatively. The patients pain 24 h postoperatively and satisfaction 48 h postoperatively was filled on an 11-point numeric rating scale (NRS).
The repeated-dose group had lower BPI severity score (p=0.045) and BPI interference score (p=0.043) mean values postoperatively compared to the three other groups separately. Also, the time effect on the linear mixed model in BPI interference score mean values was statistically significant (p=0.008), which means that in the repeated dose group preoperative BPI severity score [2.7 (3.9)] and interference score [4.3 (4.2)] mean (SD) values were significantly higher than the BPI severity score [1.3 (0.8)] and interference score [1.5 (1.8)] mean (SD) values following surgery.
The higher elevation in BPI severity score and decrease in interference score values in the repeated dose group and also the time effect in a linear mixed model in BPI interference score were statistically significant.
背景/目的:我们最初的假设是腹直肌鞘阻滞(RSB)镇痛可以提高患者满意度并减轻经腹正中切口手术后的疼痛。
最初,56 名患者被随机分为四组:对照组(n=12)、单次剂量组(n=16)、重复剂量组(n=12)和连续输注组(n=16)。在术前、术后 1 周、4 周和 12 个月进行 BPI(简明疼痛量表)调查。术后 24 小时的疼痛和 48 小时的满意度通过 11 点数字评分量表(NRS)进行评估。
与其他三组相比,重复剂量组术后 BPI 严重程度评分(p=0.045)和 BPI 干扰评分(p=0.043)平均值较低。此外,线性混合模型中 BPI 干扰评分平均值的时间效应具有统计学意义(p=0.008),这意味着在重复剂量组中,术前 BPI 严重程度评分[2.7(3.9)]和干扰评分[4.3(4.2)]的平均值明显高于术后的 BPI 严重程度评分[1.3(0.8)]和干扰评分[1.5(1.8)]。
重复剂量组的 BPI 严重程度评分升高和干扰评分降低以及 BPI 干扰评分线性混合模型中的时间效应具有统计学意义。