马郁兰的抗氧化能力及气相色谱-质谱联用分析成分
Antioxidant potency and GC-MS composition of Origanum majorana Linn.
作者信息
Prakash Nyayiru Kannaian Udaya, Sripriya Nannu Shankar, Raj Dinakaran Divakar, Deepa Santhanakrishnan, Bhuvaneswari Srinivasan
机构信息
Department of Biotechnology, Vels University, Pallavaram, Chennai, India.
Research and Development, MARINA LABS, No.14, Kavya Gardens, N.T. Patel Road, Nerkundram, Chennai, India.
出版信息
Pak J Pharm Sci. 2019 Sep;32(5):2117-2122.
The methanolic extract of the leaves of Origanum majorana L., was screened for its antioxidant potential and chemical composition. Apart from high total phenolic, flavonoid and antioxidant contents, significant free radical scavenging ability was observed as assessed by the free radical scavenging assays viz., 2,2-Diphenyl-1-picryl hydrazyl, Ferric thiocyanate, Thiobarbituric acid, Ferric reducing antioxidant power and ABTS assays. The GC-MS analysis of the methanolic extract detected the presence of seven compounds - 5H-Cyclopropa[3,4]benz[1,2-e]azulen-5-one, 3,9,9a-tris (acetyloxy)-3-[(acetyloxy)methyl]-2-chloro-1,1a,1b,2,3,4,4a,7a,7b,8,9,9a-dodecahydro-4a,7b-dihydroxy-1,1,6,8-tetrame-thyl-,[1aR-(1aa,1ba,2a,3a,4aa,7aa,7ba,8a,9a,9aa)]-; Pentacosanoic acid, methyl ester; 10-Octadecenoic acid, methyl ester; 1,2,4-Trioxolane-2-octanoic acid, 5-Octyl-, methyl ester; Oleoyl chloride; Docosanedioic acid, dimethyl ester and Ethyl iso-allocholate.
对牛至叶的甲醇提取物进行了抗氧化潜力和化学成分筛选。除了具有较高的总酚、黄酮和抗氧化含量外，通过自由基清除试验（即2,2-二苯基-1-苦基肼、硫氰酸铁、硫代巴比妥酸、铁还原抗氧化能力和ABTS试验）评估，观察到其具有显著的自由基清除能力。甲醇提取物的气相色谱-质谱分析检测到七种化合物的存在——5H-环丙并[3,4]苯并[1,2-e]薁-5-酮、3,9,9a-三（乙酰氧基）-3-[(乙酰氧基)甲基]-2-氯-1,1a,1b,2,3,4,4a,7a,7b,8,9,9a-十二氢-4a,7b-二羟基-1,1,6,8-四甲基-[1aR-(1aa,1ba,2a,3a,4aa,7aa,7ba,8a,9a,9aa)]-；二十五烷酸甲酯；10-十八碳烯酸甲酯；1,2,4-三氧杂环戊烷-2-辛酸，5-辛基-，甲酯；油酰氯；二十二碳二酸二甲酯和异乙基别胆酸盐。
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