Department of Occupational and Environmental Medicine, University Hospital of North Norway, Tromsø, Norway.
Institute of Community Medicine, UiT- The Arctic University of Norway, Tromsø, Norway.
PLoS One. 2019 Dec 12;14(12):e0226221. doi: 10.1371/journal.pone.0226221. eCollection 2019.
Health effects of traffic-related air pollution (TRAP) concentrations in densely populated areas are previously described. However, there is still a lack of knowledge of the health effects of moderate TRAP levels. The aim of the current study, a population-based survey including 16 099 adults (response rate 33%), was to assess the relationship between TRAP estimates and respiratory symptoms in an area with modest levels of traffic; Telemark County, Norway. Respondents reported respiratory symptoms the past 12 months and two TRAP exposure estimates: amount of traffic outside their bedroom window and time spent by foot daily along a moderate to heavy traffic road. Females reported on average more symptoms than males. Significant relationships between traffic outside their bedroom window and number of symptoms were only found among females, with the strongest associations among female occasional smokers (incidence rate ratio [IRR], 1.75, 95% confidence interval (CI) [1.16-2.62] for moderate or heavy traffic compared to no traffic). Significant relationship between time spent daily by foot along a moderate to heavy traffic road and number of symptoms was found among male daily smokers (IRR 1.09, 95% CI [1.04-1.15] per hour increase). Associations between traffic outside bedroom window and each respiratory symptom were found. Significant associations were primarily detected among females, both among smokers and non-smokers. Significant associations between time spent by foot daily along a moderate to heavy traffic road (per hour) and nocturnal dyspnoea (odds ratio (OR) 1.20, 95% CI [1.05-1.38]), nocturnal chest tightness (OR 1.13 [1.00-1.28]) and wheezing (OR 1.14 [1.02-1.29]) were found among daily smokers, primarily men. Overall, we found significant associations between self-reported TRAP exposures and respiratory symptoms. Differences between genders and smoking status were identified. The findings indicate an association between TRAP and respiratory symptoms even in populations exposed to modest levels of TRAP.
交通相关空气污染(TRAP)浓度对人口稠密地区的健康影响此前已有描述。然而,对于中等 TRAP 水平的健康影响,我们仍缺乏了解。本研究是一项基于人群的调查,共纳入 16099 名成年人(应答率为 33%),目的是评估交通适度地区 TRAP 估计值与呼吸症状之间的关系;挪威特伦马克县。受访者报告了过去 12 个月的呼吸症状,以及两种 TRAP 暴露估计值:卧室窗外的交通量和每天沿着中等至繁忙交通道路步行的时间。女性报告的症状平均多于男性。仅在女性中发现卧室窗外的交通量与症状数量之间存在显著关系,在女性偶尔吸烟者中最强(发病率比 [IRR],与无交通相比,中度或重度交通为 1.75,95%置信区间 [95%CI] [1.16-2.62])。每天沿着中等至繁忙交通道路步行与症状数量之间存在显著关系的是男性每日吸烟者(IRR 1.09,95%CI [1.04-1.15]每小时增加)。在卧室窗外的交通量与每个呼吸症状之间发现了关联。在女性中,无论是吸烟者还是非吸烟者,主要发现了显著的关联。每天沿着中等至繁忙交通道路步行(每小时)与夜间呼吸困难(比值比 [OR] 1.20,95%CI [1.05-1.38])、夜间胸闷(OR 1.13 [1.00-1.28])和喘息(OR 1.14 [1.02-1.29])之间存在显著关联,主要是男性。总的来说,我们发现自我报告的 TRAP 暴露与呼吸症状之间存在显著关联。确定了性别和吸烟状况之间的差异。研究结果表明,即使在暴露于中等水平 TRAP 的人群中,TRAP 与呼吸症状之间也存在关联。