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儿童湿疹和/或食物过敏与钙摄入量的前瞻性队列研究。

Calcium Intake in Children with Eczema and/or Food Allergy: A Prospective Cohort Study.

机构信息

Max Rady College of Medicine, The University of Manitoba, Winnipeg, MB R3E 0W2, Canada.

Department of Pediatrics and Child Health, The University of Manitoba, Winnipeg, MB R3E 0W2, Canada.

出版信息

Nutrients. 2019 Dec 12;11(12):3039. doi: 10.3390/nu11123039.

Abstract

Eczema and food allergy may impact diet. Using data from a cohort of Manitoba children born in 1995, we examined calcium intake, defined as the frequency and quality of calcium products consumed (with the exception of cheese), amongst Manitoba adolescents (12-14 years) with eczema or food allergy in childhood (7-8 years) or adolescence. At both ages, children were assessed by a physician for eczema and food allergy. Adolescents completed food frequency questionnaires. Calcium intake was defined as 1+ vs. <1 weekly. Linear and logistic regression was used as appropriate, with adjustments for confounders. Overall, 468 adolescents were included, of whom 62 (13.3%) had eczema only in childhood, 25 (5.3%) had food allergy only, and 26 (5.6%) had eczema and food allergy. Compared to children without eczema, those with eczema only had poorer calcium intake in adolescence (β -0.44; 95%CI -0.96; 0.00). Girls, but not boys, with eczema in childhood had poorer calcium intake in adolescence than girls without eczema (β -0.84; 95%CI -1.60; -0.08). These patterns persisted even if children experienced transient vs. persistent eczema to adolescence. Similar but non-significant trends were found for food allergy. Childhood eczema is associated with significantly lower calcium intake and consumption in adolescence. These differences persist to adolescence, even if a child "outgrows" their allergic condition.

摘要

特应性皮炎和食物过敏可能会影响饮食。本研究使用 1995 年曼尼托巴出生队列的数据,调查了曼尼托巴青少年(12-14 岁)中特应性皮炎或食物过敏(7-8 岁)或青春期(12-14 岁)儿童的钙摄入量,定义为钙产品的摄入频率和质量(除奶酪外)。在两个年龄组中,均由医生评估儿童的特应性皮炎和食物过敏情况。青少年完成食物频率问卷。钙摄入量定义为每周摄入≥1 次和<1 次。线性和逻辑回归是合适的,调整了混杂因素。总体而言,纳入了 468 名青少年,其中 62 名(13.3%)仅在儿童期患有特应性皮炎,25 名(5.3%)仅患有食物过敏,26 名(5.6%)患有特应性皮炎和食物过敏。与无特应性皮炎的儿童相比,仅在儿童期患有特应性皮炎的儿童在青春期的钙摄入量较差(β-0.44;95%CI-0.96;0.00)。患有特应性皮炎的女孩,无论性别,在青春期的钙摄入量均低于无特应性皮炎的女孩(β-0.84;95%CI-1.60;-0.08)。即使儿童在青春期经历了特应性皮炎的短暂发作或持续发作,这些模式仍然存在。对于食物过敏,也存在类似但无统计学意义的趋势。儿童期特应性皮炎与青春期钙摄入量和摄入显著降低相关。即使儿童“摆脱”了过敏状态,这些差异仍会持续到青春期。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acfe/6950300/3a0c0f71bf28/nutrients-11-03039-g001.jpg

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