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基于 PSMA 的治疗策略:mCRPC 患者诊断与治疗的实用分步方法。

PSMA-Based Theranostics: A Step-by-Step Practical Approach to Diagnosis and Therapy for mCRPC Patients.

机构信息

Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany.

Department of Nuclear Medicine, University Hospital Munster, Bonn, Germany.

出版信息

Semin Nucl Med. 2020 Jan;50(1):98-109. doi: 10.1053/j.semnuclmed.2019.07.003. Epub 2019 Aug 21.

Abstract

To date, several papers have been published about prostate-specific membrane antigen (PSMA)-based radioligand diagnostic and therapeutic approaches. This paper mainly provides information for nuclear medicine physicians that are clinically engaged in the diagnosis and treatment of prostate cancer patients. It aims to present the utility of PSMA imaging and therapy in a step-by-step practical approach; thus, it does not discuss radiochemistry and the molecular basics of PSMA.

摘要

迄今为止,已经发表了几篇关于前列腺特异性膜抗原(PSMA)为基础的放射性配体诊断和治疗方法的论文。本文主要为临床参与前列腺癌患者诊断和治疗的核医学医师提供信息。它旨在以逐步实用的方法介绍 PSMA 成像和治疗的应用;因此,本文不讨论放射化学和 PSMA 的分子基础。

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