基于 X 染色体 Alu 插入标记的西北印度人群的遗传特征。
Genetic portrait of North-West Indian population based on X chromosome Alu insertion markers.
机构信息
Department of Anthropology, Panjab University, Chandigarh, India.
Department of Human Genetics, Guru Nanak Dev University, Amritsar, Punjab, India.
出版信息
Int J Legal Med. 2020 Sep;134(5):1655-1657. doi: 10.1007/s00414-019-02238-3. Epub 2019 Dec 18.
In the present study, allele frequencies and forensic parameters of four ethnic groups (Brahmin, Khatri, Jat Sikh, and Scheduled Caste) of Punjab, India, at 10 Alu insertions of X chromosome were calculated. Six Alu markers were observed to be highly polymorphic with no significant deviations from Hardy-Weinberg equilibrium and no linkage disequilibrium present in any marker. Multidimensional plot showed higher genetic affinity of studied populations with Asian populations. Overall, the tested markers were reliable and were found suitable in human forensics and population genetic studies.
在本研究中，计算了印度旁遮普邦四个族群（婆罗门、卡提里、锡克教徒贾特和在册种姓）的 X 染色体上 10 个 Alu 插入的等位基因频率和法医参数。观察到六个 Alu 标记高度多态性，与 Hardy-Weinberg 平衡没有显著偏差，任何标记都没有存在连锁不平衡。多维图显示，研究人群与亚洲人群具有更高的遗传亲和力。总的来说，测试的标记是可靠的，并且在法医和人群遗传学研究中是适用的。
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