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影响宫颈癌患者生活质量的因素:一项多变量分析。

Factors affecting quality of life of cervical cancer patients: A multivariate analysis.

作者信息

Singh Uma, Verma Manju Lata, Rahman Zakia, Qureshi Sabuhi, Srivastava Kirti

机构信息

Department of Obstetrics and Gynaecology, KGMU, Lucknow, Uttar Pradesh, India.

Department of Radiotherapy, KGMU, Lucknow, Uttar Pradesh, India.

出版信息

J Cancer Res Ther. 2019 Oct-Dec;15(6):1338-1344. doi: 10.4103/jcrt.JCRT_1028_17.

Abstract

OBJECTIVE

The aim of good management for cancer survivors should not be limited to only clinical care, but rather it should also include best quality of life (QOL). The objective of this study was to find out various factors affecting QOL in cervical cancer patients so that by modifying these factors, the best QOL can be provided to them.

MATERIALS AND METHODS

This was a prospective cohort study conducted in the Department of Obstetrics and Gynaecology and Department of Radiotherapy, King George's Medical University (KGMU), Lucknow, from May 2015 to July 2016. The cases were selected from patients visiting the outpatient department or who were admitted to the Department of Obstetrics and Gynaecology and Department of Radiotherapy, KGMU. The data information was collected in the form of face-to-face interview using European Organization for Research and Treatment of Cancer general cancer QOL Score 30 (EORTC QLQ C-30) and EORTC QOL questionnaire cervical cancer module (QLQ CX-24) questionnaire.

RESULTS

QOL was assessed in 85 patients. Health-related QOL was separately studied in terms of overall general QOL and cancer cervix-specific QOL, and various factors affecting QOL were studied by multivariate analysis.

CONCLUSION

Education, tobacco use, degree of differentiation of tumor, and size of tumor were the independent factors found to have statistically significant effect on QOL of cervical cancer survivors.

摘要

目的

癌症幸存者的良好管理目标不应仅限于临床护理,还应包括最佳生活质量(QOL)。本研究的目的是找出影响宫颈癌患者生活质量的各种因素,以便通过改变这些因素,为他们提供最佳生活质量。

材料与方法

这是一项前瞻性队列研究,于2015年5月至2016年7月在勒克瑙乔治国王医科大学(KGMU)妇产科和放疗科进行。病例选自前往门诊就诊或入住KGMU妇产科和放疗科的患者。数据信息通过面对面访谈的形式收集,使用欧洲癌症研究与治疗组织通用癌症生活质量评分30(EORTC QLQ C - 30)和EORTC生活质量问卷宫颈癌模块(QLQ CX - 24)问卷。

结果

对85例患者的生活质量进行了评估。从总体一般生活质量和宫颈癌特异性生活质量方面分别研究了与健康相关的生活质量,并通过多变量分析研究了影响生活质量的各种因素。

结论

教育程度、吸烟情况、肿瘤分化程度和肿瘤大小是发现对宫颈癌幸存者生活质量有统计学显著影响的独立因素。

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