Velanovich V, Smith D J, Robson M C, Heggers J P
Letterman Army Medical Center, San Francisco, California.
Am Surg. 1988 Nov;54(11):659-63.
There has been experimental information suggesting that iatrogenic anemia may improve the survival of pedicled free flaps. This has been attributed to a decrease in blood viscosity secondary to hemodilution. The hemoglobin (Hb) and hematocrit (Hct) levels of 14 successful and 6 failed free flaps at the time of operation, during hospitalization, and at discharge are reviewed. There was no difference in Hb or Hct levels between successful and failed flaps. Reconstruction of traumatic defects showed an increased risk of failure. If flaps survived longer than 10-14 days, they were unlikely to fail subsequently. In conclusion, Hb and Hct levels in clinically acceptable ranges have no effect on free flap survival.
有实验信息表明,医源性贫血可能会提高带蒂游离皮瓣的存活率。这归因于血液稀释导致的血液粘度降低。回顾了14例成功和6例失败游离皮瓣在手术时、住院期间及出院时的血红蛋白(Hb)和血细胞比容(Hct)水平。成功和失败皮瓣的Hb或Hct水平没有差异。创伤性缺损的重建显示失败风险增加。如果皮瓣存活超过10 - 14天,随后不太可能失败。总之,临床可接受范围内的Hb和Hct水平对游离皮瓣存活没有影响。