Harris Vandra C, Dalesio Nicholas M, Clark James, Nellis Jason C, Tunkel David E, Lee Andrew H, Skinner Margaret
Department of Otolaryngology, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Department of Otolaryngology, Johns Hopkins Medical Institutions, Baltimore, MD, USA; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Int J Pediatr Otorhinolaryngol. 2020 Apr;131:109844. doi: 10.1016/j.ijporl.2019.109844. Epub 2019 Dec 24.
Identify incidence and factors associated with respiratory complications after type 1 cleft repair.
Retrospective chart review of patients who underwent cleft repair over a 5-year period performed by a single surgeon. Primary endpoint was respiratory complications (oxygen desaturation <90%). Fisher's exact test was used to identify differences between repair types (endoscopic carbon dioxide laser-assisted repair and injection laryngoplasty). Logistic regression was used to identify predictors of respiratory events.
Fifty-five patients were included. Thirty-four (62%) patients underwent endoscopic carbon dioxide laser-assisted repair and 21 (38%) underwent injection laryngoplasty. Average hospital stay for each group was 1.6 days (SD = 3.1) and 0.6 days (SD = 0.9), respectively. Desaturations occurred in three patients (9%) in the laser-assisted repair group and one patient (4%) in the injection group. All occurred within 3 h after surgery and resolved with supplemental oxygen, oral airway placement, and/or mask ventilation. Two affected patients had comorbid diagnosis of asthma (one had poor medication compliance), and one had a history of developmental delay and hypotonia. In the injection group, desaturations occurred in one patient with a history of tracheal stenosis and double aortic arch. No correlation existed between repair type and desaturation (p = 0.57). No variables were significant predictors of events.
In this cohort, respiratory events after type 1 laryngeal cleft repair occurred early in the postoperative period, in children with cardiac and pulmonary comorbidities. This suggests postoperative admission may only be necessary for a select group of patients undergoing type 1 cleft repair. However, further research is needed to determine criteria for same-day discharge.
确定1型腭裂修复术后呼吸并发症的发生率及相关因素。
对由一名外科医生在5年期间内进行腭裂修复手术的患者进行回顾性病历审查。主要终点是呼吸并发症(氧饱和度<90%)。采用Fisher精确检验来确定修复类型(内镜二氧化碳激光辅助修复和注射喉成形术)之间的差异。使用逻辑回归来确定呼吸事件的预测因素。
纳入55例患者。34例(62%)患者接受了内镜二氧化碳激光辅助修复,21例(38%)接受了注射喉成形术。每组的平均住院时间分别为1.6天(标准差=3.1)和0.6天(标准差=0.9)。激光辅助修复组有3例患者(9%)出现氧饱和度下降,注射组有1例患者(4%)出现氧饱和度下降。所有这些情况均发生在术后3小时内,并通过补充氧气、放置口咽通气道和/或面罩通气得到缓解。两名受影响的患者合并哮喘诊断(其中一名药物依从性差),一名有发育迟缓及肌张力减退病史。在注射组中,一名有气管狭窄和双主动脉弓病史的患者出现了氧饱和度下降。修复类型与氧饱和度下降之间无相关性(p = 0.57)。没有变量是事件的显著预测因素。
在该队列中,1型喉裂修复术后的呼吸事件发生在术后早期,见于有心脏和肺部合并症的儿童。这表明可能仅对接受1型腭裂修复的特定患者群体有必要进行术后住院。然而,需要进一步研究以确定当日出院的标准。