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印度北部一家三级护理医院超重和肥胖人群中慢性肾脏病的患病率及危险因素

Prevalence and risk factors of chronic kidney disease in overweight and obese population in a tertiary care hospital in North India.

作者信息

Rai Pradeep Kumar, Rai Punam, Bedi Sonam

机构信息

Department of Nephrology, Opal Hospital, Kakarmatta, Uttar Pradesh, India.

Department of Clinical Physiology, Opal Hospital, Kakarmatta, Uttar Pradesh, India.

出版信息

Saudi J Kidney Dis Transpl. 2019 Nov-Dec;30(6):1431-1438. doi: 10.4103/1319-2442.275488.

Abstract

Obesity has already been a global epidemic, and its prevalence has been projected to grow by 40% in the next decade. Its increasing prevalence has implications on the epidemiology of chronic kidney disease (CKD), which, in turn, could impact the health system and thereby the society in an adverse manner. Lack of community-based screening programs can lead to missed or late detection of CKD. The current study aims to estimate the prevalence of CKD in overweight and obese general population attending a screening camp in a tertiary care hospital in a North Indian city. In this cross-sectional study, 103 overweight and obese people from a community attending a health camp were screened for serum creatinine, urine analysis, random blood sugar, and uric acid. Demographic and anthropometric parameters were noted. Binary logistic regression analysis was used to find the predictors of CKD in these patients. The median age of the participants was 43 years with a male predominance (68%). More than half (58.4%) of the participants were obese and the remaining 41.6% were overweight. The overall prevalence of CKD was 17.5%. Individuals with obesity and diabetes were more prone to develop CKD (odds ratio = 4.868 and 7.941, respectively). CKD was prevalent in individuals with obesity. Obesity and diabetes were the significant predictors for the development of CKD. All the overweight and obese individuals should be periodically screened for kidney diseases.

摘要

肥胖已经成为一种全球流行病,预计其患病率在未来十年将增长40%。其患病率的不断上升对慢性肾脏病(CKD)的流行病学产生影响,进而可能对卫生系统乃至社会产生不利影响。缺乏基于社区的筛查项目可能导致CKD的漏诊或延迟诊断。本研究旨在估计在印度北部城市一家三级护理医院参加筛查营的超重和肥胖普通人群中CKD的患病率。在这项横断面研究中,对来自社区参加健康营的103名超重和肥胖者进行了血清肌酐、尿液分析、随机血糖和尿酸筛查。记录了人口统计学和人体测量学参数。采用二元逻辑回归分析来找出这些患者中CKD的预测因素。参与者的中位年龄为43岁,男性占多数(68%)。超过一半(58.4%)的参与者肥胖,其余41.6%超重。CKD的总体患病率为17.5%。肥胖和糖尿病患者更易患CKD(优势比分别为4.868和7.941)。肥胖个体中CKD普遍存在。肥胖和糖尿病是CKD发生的重要预测因素。所有超重和肥胖个体都应定期进行肾脏疾病筛查。

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