School of Computer and Communication Engineering, University of Science and Technology Beijing, Beijing, 100083, China.
Department of Thoracic Surgery, Chinese PLA General Hospital, Beijing, 100853, China.
Med Biol Eng Comput. 2020 Apr;58(4):709-724. doi: 10.1007/s11517-020-02128-6. Epub 2020 Jan 18.
The accurate modeling of the liver vessel network structure is an important prerequisite for developing a preoperative plan for the liver. Considering that extracting liver blood vessels from patient's abdominal computed tomography(CT) images requires several manual operations, this study proposed an automatic segmentation method of liver vessels based on graph cut, thinning, and vascular combination, which can obtain a complete liver vascular network. First, the CT image was preprocessed by grayscale mapping based on sigmoid function, vessel enhancement based on Hessian filter, and denoising based on anisotropic filter to enhance the grayscale contrast between the vascular and non-vascular parts of the liver. Then, the liver vessels were initially segmented based on the improved three-dimensional graph cut algorithm. Based on the obtained liver vascular structure, the vessel centerline of the liver was then extracted by the proposed thinning algorithm that continuously traversed the foreground voxel points and iteratively deleted the simple points. Finally, the combination of vascular centerline optimization was used to predict and link the vascular centerline fractured portion. The under-segmented liver vessels were complemented based on the complete vascular centerline tree. To verify the proposed hepatic vascular segmentation and complementation algorithm, the open 3D Image Reconstruction for Comparison of Algorithm Database (3Dircadb) was applied to test and quantify the results. The results showed that the proposed algorithm can accurately and effectively segment the vascular network structure from abdominal CT images, and the proposed vascular complementation method can restore the true information of under-segmented liver vessels. Graphical abstract A novel hepatic vessel segmentation method from abdominal CT images was proposed, including graph cut algorithm, centerline extraction, and broken vessel completion. First, the graph cut algorithm was used to obtain the initial segmentation result. Then, the centerline of the initial segmentation result was extracted. Finally, the initial segmentation result was optimized through centerline analysis.
肝脏血管网络结构的精确建模是制定肝脏术前计划的重要前提。考虑到从患者腹部 CT 图像中提取肝脏血管需要进行多次手动操作,本研究提出了一种基于图割、细化和血管组合的肝脏血管自动分割方法,可以获得完整的肝脏血管网络。首先,通过基于 sigmoid 函数的灰度映射、基于 Hessian 滤波器的血管增强和基于各向异性滤波器的去噪对 CT 图像进行预处理,以增强肝脏血管和非血管部分的灰度对比度。然后,基于改进的三维图割算法对肝脏血管进行初步分割。基于获得的肝脏血管结构,通过提出的细化算法提取肝脏血管中心线,该算法通过连续遍历前景体素点并迭代删除简单点来实现。最后,采用血管中心线优化组合,预测和连接断裂的血管中心线部分。基于完整的血管中心线树来补充欠分割的肝脏血管。为了验证所提出的肝脏血管分割和补充算法,应用开放的 3D Image Reconstruction for Comparison of Algorithm Database (3Dircadb) 进行测试和量化结果。结果表明,所提出的算法可以准确有效地从腹部 CT 图像中分割血管网络结构,所提出的血管补充方法可以恢复欠分割肝脏血管的真实信息。
本研究提出了一种从腹部 CT 图像中提取肝脏血管的新方法,包括图割算法、中心线提取和血管断裂补充。首先,使用图割算法获得初始分割结果。然后,提取初始分割结果的中心线。最后,通过中心线分析对初始分割结果进行优化。